BRENDA - Enzyme Database show
show all sequences of 1.7.1.6

Characterization and purification of membrane-bound azoreductase from azo dye degrading Shewanella sp. strain IFN4

Imran, M.; Negm, F.; Hussain, S.; Ashraf, M.; Ashraf, M.; Ahmad, Z.; Arshad, M.; Crowley, D.; CSAWAC 44, 1523-1530 (2016)
No PubMed abstract available

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
anthraquinone-2,6-disulfonic acid
activates about 2.5fold
Shewanella sp. IFN4
anthraquinone-2-sulfonic acid
activates about 3fold
Shewanella sp. IFN4
additional information
the enzyme is stimulated on the addition of flavin or quinone compounds. Supplementation of the azoreductase assay with redox active substances (riboflavin, anthraquinone-2,6-disulfonic acid, and anthraquinone-2-sulfonic acid) increases the specific activity of membrane-bound azoreductase as the shuttling of electrons to azo substrate is promoted
Shewanella sp. IFN4
riboflavin
activates about 2fold
Shewanella sp. IFN4
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
additional information
the azoreductase of the Shewanella sp. strain IFN4 reduces the azo dyes extracellularly while being attached with the plasma membrane
Shewanella sp. IFN4
-
-
plasma membrane
membrane-bound azoreductase
Shewanella sp. IFN4
5886
-
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
33000
-
native PAGE
Shewanella sp. IFN4
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Shewanella sp. IFN4
-
-
-
Purification (Commentary)
Commentary
Organism
39.3fold by ammonium sulfate fractionation and anion exchange chromatography
Shewanella sp. IFN4
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
3.55
-
pH 8.0, 45°C, crude enzyme, substrate reactive black 5
Shewanella sp. IFN4
139.63
-
pH 8.0, 45°C, purified enzyme, substrate reactive black 5
Shewanella sp. IFN4
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
acid red 88 + NADPH + H+
-
742324
Shewanella sp. IFN4
? + NADP+
-
-
-
?
acid yellow 19 + NADPH + H+
low activity
742324
Shewanella sp. IFN4
? + NADP+
-
-
-
?
direct red 81 + NADPH + H+
-
742324
Shewanella sp. IFN4
? + NADP+
-
-
-
?
disperse orange 3 + NADPH + H+
-
742324
Shewanella sp. IFN4
? + NADP+
-
-
-
?
additional information
wide substrate specificity of the enzyme. No activity with reactive blue 4
742324
Shewanella sp. IFN4
?
-
-
-
-
reactive black 5 + NADPH + H+
best substrate
742324
Shewanella sp. IFN4
? + NADP+
-
-
-
?
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
45
-
-
Shewanella sp. IFN4
Temperature Range [°C]
Temperature Minimum [°C]
Temperature Maximum [°C]
Commentary
Organism
4
70
activity range, profile overview, inactive at 80°C
Shewanella sp. IFN4
Temperature Stability [°C]
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
4
50
partially purified enzyme, pH 8.0, 30 min, stable at
Shewanella sp. IFN4
55
-
partially purified enzyme, pH 8.0, 30 min, 50% of maximal activity remaining
Shewanella sp. IFN4
70
-
partially purified enzyme, pH 8.0, 30 min, inactivation
Shewanella sp. IFN4
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8
-
-
Shewanella sp. IFN4
pH Range
pH Minimum
pH Maximum
Commentary
Organism
5
9.5
activity range, profile overview
Shewanella sp. IFN4
Cofactor
Cofactor
Commentary
Organism
Structure
NADPH
-
Shewanella sp. IFN4
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
anthraquinone-2,6-disulfonic acid
activates about 2.5fold
Shewanella sp. IFN4
anthraquinone-2-sulfonic acid
activates about 3fold
Shewanella sp. IFN4
additional information
the enzyme is stimulated on the addition of flavin or quinone compounds. Supplementation of the azoreductase assay with redox active substances (riboflavin, anthraquinone-2,6-disulfonic acid, and anthraquinone-2-sulfonic acid) increases the specific activity of membrane-bound azoreductase as the shuttling of electrons to azo substrate is promoted
Shewanella sp. IFN4
riboflavin
activates about 2fold
Shewanella sp. IFN4
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NADPH
-
Shewanella sp. IFN4
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
additional information
the azoreductase of the Shewanella sp. strain IFN4 reduces the azo dyes extracellularly while being attached with the plasma membrane
Shewanella sp. IFN4
-
-
plasma membrane
membrane-bound azoreductase
Shewanella sp. IFN4
5886
-
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
33000
-
native PAGE
Shewanella sp. IFN4
Purification (Commentary) (protein specific)
Commentary
Organism
39.3fold by ammonium sulfate fractionation and anion exchange chromatography
Shewanella sp. IFN4
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
3.55
-
pH 8.0, 45°C, crude enzyme, substrate reactive black 5
Shewanella sp. IFN4
139.63
-
pH 8.0, 45°C, purified enzyme, substrate reactive black 5
Shewanella sp. IFN4
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
acid red 88 + NADPH + H+
-
742324
Shewanella sp. IFN4
? + NADP+
-
-
-
?
acid yellow 19 + NADPH + H+
low activity
742324
Shewanella sp. IFN4
? + NADP+
-
-
-
?
direct red 81 + NADPH + H+
-
742324
Shewanella sp. IFN4
? + NADP+
-
-
-
?
disperse orange 3 + NADPH + H+
-
742324
Shewanella sp. IFN4
? + NADP+
-
-
-
?
additional information
wide substrate specificity of the enzyme. No activity with reactive blue 4
742324
Shewanella sp. IFN4
?
-
-
-
-
reactive black 5 + NADPH + H+
best substrate
742324
Shewanella sp. IFN4
? + NADP+
-
-
-
?
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
45
-
-
Shewanella sp. IFN4
Temperature Range [°C] (protein specific)
Temperature Minimum [°C]
Temperature Maximum [°C]
Commentary
Organism
4
70
activity range, profile overview, inactive at 80°C
Shewanella sp. IFN4
Temperature Stability [°C] (protein specific)
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
4
50
partially purified enzyme, pH 8.0, 30 min, stable at
Shewanella sp. IFN4
55
-
partially purified enzyme, pH 8.0, 30 min, 50% of maximal activity remaining
Shewanella sp. IFN4
70
-
partially purified enzyme, pH 8.0, 30 min, inactivation
Shewanella sp. IFN4
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8
-
-
Shewanella sp. IFN4
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
5
9.5
activity range, profile overview
Shewanella sp. IFN4
General Information
General Information
Commentary
Organism
additional information
the azoreductase of the Shewanella sp. strain IFN4 reduces the azo dyes extracellularly while being attached with the plasma membrane. Electrons generated by cellular metabolism must be transported outside the cell in order to reduce substrate. Electrons are transferred from the menaquinone pool in the cytoplasmic membrane to the bacterial cell surface through a series of proteins. Shewanella sp. secretes redox-active flavin compounds able to transfer electrons between the cell surface and substrate in a cyclic fashion, a process termed electron shuttling. In the absence of redox-active flavin compounds transfer of electrons to the substrate is a slow process. Therefore, supplementation of the azoreductase assay with redox active substances (riboflavin, anthraquinone-2,6-disulfonic acid, and anthraquinone-2-sulfonic acid) increases the specific activity of membrane-bound azoreductase as the shuttling of electrons to azo substrate is promoted
Shewanella sp. IFN4
physiological function
the enzyme is identified as a primary functional membrane-bound azoreductase used by members of the genus Shewanella to degrade azo dyes. Complete degradation of azo dyes by bacteria occurs in two sequential steps. In the first step, reductive cleavage of the azo bond takes place under anaerobic conditions, generating colorless aromatic amines, which are further degraded by aerobic processes. The reduction step is carried out mainly by azoreductase enzymes, which then cleave the azo bond by transferring electrons from reducing equivalents (NADH or NADPH) generated from the metabolism of organic compounds to the dye molecule
Shewanella sp. IFN4
General Information (protein specific)
General Information
Commentary
Organism
additional information
the azoreductase of the Shewanella sp. strain IFN4 reduces the azo dyes extracellularly while being attached with the plasma membrane. Electrons generated by cellular metabolism must be transported outside the cell in order to reduce substrate. Electrons are transferred from the menaquinone pool in the cytoplasmic membrane to the bacterial cell surface through a series of proteins. Shewanella sp. secretes redox-active flavin compounds able to transfer electrons between the cell surface and substrate in a cyclic fashion, a process termed electron shuttling. In the absence of redox-active flavin compounds transfer of electrons to the substrate is a slow process. Therefore, supplementation of the azoreductase assay with redox active substances (riboflavin, anthraquinone-2,6-disulfonic acid, and anthraquinone-2-sulfonic acid) increases the specific activity of membrane-bound azoreductase as the shuttling of electrons to azo substrate is promoted
Shewanella sp. IFN4
physiological function
the enzyme is identified as a primary functional membrane-bound azoreductase used by members of the genus Shewanella to degrade azo dyes. Complete degradation of azo dyes by bacteria occurs in two sequential steps. In the first step, reductive cleavage of the azo bond takes place under anaerobic conditions, generating colorless aromatic amines, which are further degraded by aerobic processes. The reduction step is carried out mainly by azoreductase enzymes, which then cleave the azo bond by transferring electrons from reducing equivalents (NADH or NADPH) generated from the metabolism of organic compounds to the dye molecule
Shewanella sp. IFN4
Other publictions for EC 1.7.1.6
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
742203
Chalansonnet
Identification of Enterococcu ...
Enterococcus faecalis
BMC Microbiol.
17
126
2017
-
-
1
-
-
-
-
-
-
-
-
-
-
4
-
-
1
-
-
-
-
-
2
1
1
-
1
-
1
-
-
4
-
-
-
-
-
1
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
2
1
1
-
1
-
1
-
-
-
-
2
2
-
-
-
742211
Ryan
-
Azoreductases in drug metabol ...
Bacillus sp. B29, Bacillus subtilis, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa, Pseudomonas putida, Rhodobacter sphaeroides
Br. J. Pharmacol.
174
2161-2173
2017
-
7
7
3
-
-
7
-
7
-
-
-
-
7
-
-
-
7
-
-
-
-
11
1
-
-
-
-
-
-
-
8
-
-
-
-
7
7
8
3
-
-
-
7
-
-
7
-
-
-
-
-
-
-
-
-
-
-
11
1
-
-
-
-
-
-
-
-
-
15
15
-
-
-
742393
Liu
Exclusive extracellular biore ...
Geobacter sulfurreducens, Geobacter sulfurreducens PCA
Environ. Sci. Technol.
51
8616-8623
2017
-
1
-
-
1
-
-
1
1
-
-
2
-
5
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
1
-
1
-
-
-
-
1
1
-
-
2
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
3
3
-
-
-
742660
Rathod
-
Efficient approach to enhance ...
Enterococcus sp., Enterococcus sp. L2
Int. Biodeter. Biodegrad.
124
91-100
2017
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
15
-
-
-
-
-
1
-
-
2
-
-
-
-
-
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
15
-
-
-
-
-
1
-
-
-
-
1
1
-
-
-
741799
Mani
-
Accelerated production of oxy ...
Pseudomonas sp. B1
Asian J. Chem.
28
2562-2570
2016
-
-
-
-
-
-
-
2
1
-
1
-
-
1
1
-
1
-
-
1
1
-
1
1
1
1
-
-
1
1
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
2
1
-
1
-
-
1
-
1
-
1
1
-
1
1
1
1
-
-
1
1
-
-
-
1
1
-
-
-
742324
Imran
-
Characterization and purifica ...
Shewanella sp. IFN4
CSAWAC
44
1523-1530
2016
4
-
-
-
-
-
-
-
2
-
1
-
-
1
-
-
1
-
-
-
2
-
6
-
1
1
3
-
1
1
-
1
-
-
-
4
-
-
1
-
-
-
-
-
-
-
2
-
1
-
-
-
-
1
-
-
2
-
6
-
1
1
3
-
1
1
-
-
-
2
2
-
-
-
742921
Haghshenas
Molecular dynamics study of b ...
Bacillus sp. B29
J. Biomol. Struct. Dyn.
34
453-462
2016
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
743853
Feng
-
Interaction between flavin mo ...
Escherichia coli
Spectrosc. Lett.
49
626-634
2016
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
1
-
-
-
-
-
-
-
-
1
1
-
-
-
743182
Zhang
-
Cloning and characterization ...
Shewanella xiamenensis, Shewanella xiamenensis BC01
J. Taiwan Inst. Chem. Eng.
61
97-105
2015
-
-
1
-
-
1
1
4
-
10
-
-
12
2
-
-
1
-
-
-
3
-
8
1
1
1
2
-
1
1
1
4
-
1
-
-
-
1
4
-
-
1
-
1
-
4
-
10
-
-
12
-
-
1
-
-
3
-
8
1
1
1
2
-
1
1
1
1
-
1
1
-
-
-
742663
Lu
-
Construction, expression and ...
Shewanella oneidensis, Shewanella oneidensis MR-1 / ATCC 700550
Int. Biodeter. Biodegrad.
87
81-86
2014
2
-
1
-
1
-
7
2
-
2
-
-
-
2
-
-
1
-
-
-
2
-
2
1
1
1
-
2
1
1
2
1
-
-
-
2
-
1
1
-
1
-
-
7
-
2
-
2
-
-
-
-
-
1
-
-
2
-
2
1
1
1
-
2
1
1
2
-
-
-
-
-
2
2
743650
Brissos
Improving kinetic or thermody ...
Pseudomonas putida, Pseudomonas putida MET94
PLoS ONE
9
e87209
2014
-
-
1
-
21
-
-
1
-
-
-
-
-
6
-
-
-
-
-
-
-
-
1
1
1
-
-
-
1
-
-
1
-
-
-
-
-
1
1
-
21
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
1
1
-
-
-
1
-
-
-
-
1
1
-
-
-
724384
Langer
The flavoenzyme azobenzene red ...
Escherichia coli
Biochemistry
52
4288-4295
2013
-
-
-
-
-
-
-
4
-
-
-
-
-
3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
724733
Chevalier
The first latent green fluorop ...
Escherichia coli
Chem. Commun. (Camb. )
49
8815-8817
2013
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
724864
Yang
Characterization of an efficie ...
Shewanella oneidensis, Shewanella oneidensis MR-1 / ATCC 700550
Environ. Sci. Pollut. Res. Int.
20
3232-3239
2013
-
-
1
-
-
-
1
4
-
1
1
-
6
2
-
-
-
-
-
-
2
-
4
1
-
-
-
-
1
1
-
2
-
-
-
-
-
1
2
-
-
-
-
1
-
4
-
1
1
-
6
-
-
-
-
-
2
-
4
1
-
-
-
-
1
1
-
-
-
-
-
-
4
4
726356
Aranganathan
Statistical optimization of sy ...
Pseudomonas oleovorans
Prep. Biochem. Biotechnol.
43
649-667
2013
-
1
-
-
-
-
-
-
1
-
1
-
-
2
-
-
-
-
-
-
1
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
1
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
742097
Yang
Construction of an integrated ...
Shewanella oneidensis, Shewanella oneidensis MR-1 / ATCC 700550
Biores. Technol.
130
517-521
2013
-
1
1
-
-
-
-
-
-
-
-
-
-
12
-
-
1
-
-
-
-
-
4
-
-
-
-
-
1
-
-
1
-
-
-
-
1
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
4
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
742662
Shah
-
Community genomics isolation, ...
bacterium enrichment culture clone V9DM
Int. Biodeter. Biodegrad.
79
1-8
2013
-
1
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
1
-
-
-
1
-
-
2
-
-
-
-
1
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
723925
Morrison
Identification, Isolation and ...
Clostridium perfringens
Anaerobe
18
229-234
2012
-
-
1
-
-
-
1
3
-
-
2
-
-
1
-
-
-
-
-
-
-
-
1
1
1
-
-
-
1
-
-
2
-
-
-
-
-
1
2
-
-
-
-
1
-
3
-
-
2
-
-
-
-
-
-
-
-
-
1
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
724120
Feng
Probing the NADH- and Methyl R ...
Enterococcus faecalis
Arch. Biochem. Biophys.
520
99-107
2012
-
-
1
1
13
-
-
21
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
11
-
-
-
2
-
-
-
-
-
1
2
1
13
-
-
-
-
21
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
11
-
-
-
-
-
-
-
-
21
21
724799
Devi
Homology modeling and function ...
Nostoc sp.
Interdiscip. Sci.
4
310-318
2012
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
3
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
725732
Ooi
-
Flavin-binding of azoreductase ...
Bacillus sp. (in: Bacteria), Bacillus sp. (in: Bacteria) B29
J. Mol. Catal. B
74
204-208
2012
-
-
1
-
-
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
2
-
2
1
-
-
-
-
-
-
-
2
-
-
-
-
-
1
2
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
2
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
725805
Shobana
-
Evolutionary trace analysis of ...
Bacillus subtilis
J. Proteomics Bioinform.
5
222-225
2012
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
726415
Cui
-
Purification and characterizat ...
Escherichia coli, Escherichia coli CD-2
Process Biochem.
47
544-549
2012
-
-
1
-
-
-
5
2
-
-
1
-
-
2
-
-
1
-
-
-
-
-
6
1
1
1
-
-
1
1
-
2
-
-
-
-
-
1
2
-
-
-
-
5
-
2
-
-
1
-
-
-
-
1
-
-
-
-
6
1
1
1
-
-
1
1
-
-
-
-
-
-
-
-
724007
Johansson
BTI1, an azoreductase with pH- ...
Bacillus sp. (in: Bacteria) OY1-2, Staphylococcus aureus
Appl. Environ. Microbiol.
77
4223-4225
2011
-
-
-
-
-
-
-
4
-
-
-
-
-
2
-
-
-
-
-
-
-
-
11
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
11
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
711584
Chen
Identification and molecular c ...
Pigmentiphaga kullae, Pigmentiphaga kullae K24, ATCC BAA-795
BMC Biochem.
11
13
2010
-
-
1
-
-
-
-
4
-
-
2
-
-
2
-
-
1
-
-
-
2
-
8
1
1
-
-
-
1
-
-
3
-
-
-
-
-
1
3
-
-
-
-
-
-
4
-
-
2
-
-
-
-
1
-
-
2
-
8
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
724045
Matsumoto
Characterization of thermostab ...
Geobacillus stearothermophilus
Appl. Microbiol. Biotechnol.
86
1431-1438
2010
-
-
1
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
2
-
6
1
1
-
2
-
-
-
-
4
-
-
-
-
-
1
4
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
2
-
6
1
1
-
2
-
-
-
-
-
-
-
-
-
-
-
726423
Ryan
Reaction mechanism of azoreduc ...
Pseudomonas aeruginosa
Protein Cell
1
780-790
2010
-
-
-
-
-
-
2
12
-
-
-
-
-
3
-
-
-
1
-
-
-
-
4
-
-
-
-
9
-
-
-
3
-
-
-
-
-
-
3
-
-
-
-
2
-
12
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
9
-
-
-
-
2
-
-
2
-
-
726439
Feng
Evidence for significantly enh ...
Enterococcus faecalis
Protein Pept. Lett.
17
578-584
2010
-
1
1
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
696845
Ooi
Comparative enzymatic analysis ...
Bacillus sp. B29
Biosci. Biotechnol. Biochem.
73
1209-1211
2009
-
1
1
-
-
-
-
4
-
-
2
-
-
2
-
-
1
-
-
-
3
-
16
1
2
-
-
-
1
2
-
2
-
-
-
-
2
2
4
-
-
-
-
-
-
4
-
-
2
-
-
-
-
2
-
-
4
-
16
2
2
-
-
-
2
2
-
-
-
-
-
-
-
-
697494
Punj
Purification and identificatio ...
Enterococcus faecalis
Curr. Issues Mol. Biol.
11
59-65
2009
-
-
-
-
-
-
-
4
-
-
-
-
-
2
-
-
1
-
-
-
4
-
1
-
1
-
-
-
1
-
-
3
-
-
-
-
-
-
3
-
-
-
-
-
-
4
-
-
-
-
-
-
-
1
-
-
4
-
1
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
697495
Macwana
Identification and Isolation o ...
Enterococcus faecium, Enterococcus faecium ATCC 6569
Curr. Issues Mol. Biol.
12
43-48
2009
-
-
1
-
-
-
-
3
-
-
1
-
-
6
-
-
1
-
-
-
18
-
19
1
2
-
-
2
2
-
-
3
-
-
-
-
-
2
5
-
-
-
-
-
-
4
-
-
2
-
-
-
-
1
-
-
20
-
19
1
2
-
-
4
2
-
-
-
-
-
-
-
2
2
698629
Liu
The Escherichia coli azoreduct ...
Escherichia coli
J. Bacteriol.
191
6394-6400
2009
5
-
1
-
-
-
-
4
-
-
-
-
-
1
-
-
1
-
-
-
-
-
4
1
-
-
-
4
1
-
-
2
-
-
-
5
-
1
2
-
-
-
-
-
-
4
-
-
-
-
-
-
-
1
-
-
-
-
4
1
-
-
-
4
1
-
-
-
-
-
-
-
-
-
710749
Wang
Role of tyrosine 131 in the ac ...
Pseudomonas aeruginosa
Acta Crystallogr. Sect. F
66
2-7
2009
-
-
1
1
1
-
-
8
-
-
-
-
-
2
-
-
1
-
-
-
-
-
7
-
-
-
1
8
-
-
-
2
-
-
-
-
-
1
2
1
1
-
-
-
-
8
-
-
-
-
-
-
-
1
-
-
-
-
7
-
-
-
1
8
-
-
-
-
-
-
-
-
-
-
711798
Punj
Purification and identificatio ...
Enterococcus faecalis, Enterococcus faecalis ATCC 27274
Curr. Issues Mol. Biol.
11
59-66
2009
-
-
-
-
-
-
-
3
-
-
-
-
-
4
-
-
1
-
-
-
2
-
4
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
3
-
-
-
-
-
-
3
-
-
-
-
-
-
-
1
-
-
2
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
695789
Bafana
Azoreductase and dye detoxific ...
Bacillus amyloliquefaciens, Bacillus amyloliquefaciens AB
Appl. Microbiol. Biotechnol.
77
1139-1144
2008
-
1
-
-
-
-
-
-
-
-
1
-
-
2
-
-
1
-
-
-
1
-
2
-
-
-
-
-
1
-
-
1
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
1
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
695803
Liu
Enhancing survival of Escheric ...
Rhodobacter sphaeroides
Appl. Microbiol. Biotechnol.
80
409-416
2008
-
-
1
-
-
-
1
4
-
-
-
-
-
1
-
-
1
-
-
-
-
-
4
-
1
-
-
4
2
1
-
1
1
-
-
-
-
1
1
-
-
-
-
1
1
4
-
-
-
-
-
-
-
1
-
-
-
-
4
-
1
-
-
4
2
1
-
-
-
-
-
-
-
-
696793
Sandhya
Decolorizing kinetics of a rec ...
Brevibacillus laterosporus, Brevibacillus laterosporus RRK1
Biores. Technol.
99
2187-2191
2008
-
-
1
-
-
-
-
-
-
-
1
-
-
2
-
-
1
-
-
-
2
-
10
-
-
-
-
-
1
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
2
-
10
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
696902
Liu
Site-directed mutagenesis of s ...
Rhodobacter sphaeroides
Biotechnol. Lett.
30
869-875
2008
-
-
1
-
4
-
-
23
-
-
-
-
-
1
-
-
1
-
-
-
-
-
2
-
1
1
-
-
3
-
-
3
-
-
-
-
-
1
3
-
4
-
-
-
-
23
-
-
-
-
-
-
-
1
-
-
-
-
2
-
1
1
-
-
3
-
-
-
-
-
-
-
-
-
697473
Bafana
Lateral gene transfer in phylo ...
Bacillus sp. (in: Bacteria), Bacillus sp. (in: Bacteria) OY1-2, Bacillus subtilis 168, Bacillus subtilis, Enterococcus faecalis, Escherichia coli, Geobacillus stearothermophilus, Pigmentiphaga kullae, Pigmentiphaga kullae K24, Rhodobacter sphaeroides, Rhodobacter sphaeroides AS1.1737, Staphylococcus aureus, Xenophilus azovorans, Xenophilus azovorans KF46F / DSM 13620
Comput. Biol. Chem.
32
191-197
2008
-
-
-
-
-
-
-
-
-
-
-
-
-
17
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
11
-
-
-
-
-
-
11
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
698751
Ito
Expansion of substrate specifi ...
Escherichia coli
J. Biol. Chem.
283
13889-13896
2008
-
1
1
1
3
-
1
12
-
-
1
-
-
1
-
-
1
-
-
-
-
-
4
1
-
-
-
-
-
-
-
2
-
-
-
-
1
1
2
1
3
-
-
1
-
12
-
-
1
-
-
-
-
1
-
-
-
-
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
700040
Chen
Functional role of Trp-105 of ...
Enterococcus faecalis
Microbiology
154
2659-2667
2008
-
-
1
-
6
-
-
10
-
-
1
-
-
1
-
-
1
-
-
-
-
-
1
1
1
-
-
-
1
-
-
2
-
-
-
-
-
1
2
-
6
-
-
-
-
10
-
-
1
-
-
-
-
1
-
-
-
-
1
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
671554
Xu
Fe(III)-enhanced Azo Reduction ...
Shewanella decolorationis, Shewanella decolorationis S12
Appl. Microbiol. Biotechnol.
74
1342-1349
2007
-
-
-
-
-
-
-
-
-
1
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
673224
Chen
Recent advances in azo dye deg ...
Acidaminococcus fermentans, Bacillus sp. (in: Bacteria), Bacillus sp. (in: Bacteria) OY-2, Bacillus sp. (in: Bacteria) SF, Bacillus subtilis, Bacteroides thetaiotaomicron, Bifidobacterium adolescentis, Blautia obeum, Citrobacter sp., Clostridium clostridioforme, Clostridium perfringens, Coprococcus catus, Enterococcus faecalis, Escherichia coli, Fusobacterium sp., Holdemanella biformis, Kocuria rosea, Kocuria varians, Micrococcus luteus, Pantoea agglomerans, Pigmentiphaga kullae, Pigmentiphaga kullae K24, Proteus vulgaris, Rhodobacter sphaeroides, Shigella dysenteriae, Staphylococcus aureus, Staphylococcus epidermidis, Xenophilus azovorans, Xenophilus azovorans KF46
Curr. Protein Pept. Sci.
7
101-111
2006
-
-
-
-
-
-
-
-
-
-
17
-
-
30
-
-
-
-
-
-
-
-
64
9
10
-
-
-
10
-
-
17
-
-
-
-
-
-
17
-
-
-
-
-
-
-
-
-
17
-
-
-
-
-
-
-
-
-
64
9
10
-
-
-
10
-
-
-
-
-
-
-
-
-
674607
Ito
Three-dimensional structure of ...
Escherichia coli
J. Biol. Chem.
281
20567-20576
2006
-
-
-
1
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
658574
Nachiyar
-
Purification and characterizat ...
Pseudomonas aeruginosa
Enzyme Microb. Technol.
36
503-509
2005
-
1
-
-
-
-
3
2
-
-
1
-
-
1
-
-
1
-
-
-
-
-
7
1
1
1
-
-
1
1
-
1
-
-
-
-
1
-
1
-
-
-
-
3
-
2
-
-
1
-
-
-
-
1
-
-
-
-
7
1
1
1
-
-
1
1
-
-
-
-
-
-
-
-
671417
Ramalho
Azo reductase activity of inta ...
Saccharomyces cerevisiae
Appl. Environ. Microbiol.
71
3882-3888
2005
-
-
-
-
-
-
1
-
1
-
-
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
675826
Chen
Biochemical and molecular char ...
Staphylococcus aureus
Microbiology
151
1433-1441
2005
-
-
1
-
-
-
-
2
-
-
2
-
-
6
-
-
1
-
-
-
2
-
6
1
-
-
-
-
-
-
-
2
-
-
-
-
-
1
2
-
-
-
-
-
-
2
-
-
2
-
-
-
-
1
-
-
2
-
6
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
657603
Maier
A new alkali-thermostable azor ...
Bacillus sp. (in: Bacteria), Bacillus sp. (in: Bacteria) SF
Appl. Environ. Microbiol.
70
837-844
2004
-
1
-
-
-
-
1
-
-
-
1
-
-
3
-
-
1
-
-
-
-
-
12
-
1
-
3
-
1
-
-
2
-
1
-
-
1
-
2
-
-
-
-
1
-
-
-
-
1
-
-
-
-
1
-
-
-
-
12
-
1
-
3
-
1
-
-
1
-
-
-
-
-
-
658773
Yan
Expression and characteristics ...
Rhodobacter sphaeroides, Rhodobacter sphaeroides AS1.1737
FEMS Microbiol. Lett.
236
129-136
2004
-
1
1
-
-
-
2
4
-
2
2
-
-
3
-
-
1
-
-
-
6
-
12
-
2
1
-
-
-
-
-
1
-
-
-
-
1
1
1
-
-
-
-
2
-
4
-
2
2
-
-
-
-
1
-
-
6
-
12
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
660430
Chen
Molecular cloning, overexpress ...
Enterococcus faecalis
Protein Expr. Purif.
34
302-310
2004
-
-
1
-
-
-
-
2
-
-
2
1
-
6
-
-
1
-
-
-
1
-
7
1
-
-
-
-
-
-
-
2
-
1
-
-
-
1
2
-
-
-
-
-
-
2
-
-
2
1
-
-
-
1
-
-
1
-
7
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
657620
Bluemel
Cloning and characterization o ...
Pigmentiphaga kullae, Pigmentiphaga kullae K24
Appl. Microbiol. Biotechnol.
62
186-190
2003
-
1
1
-
-
-
-
-
-
-
2
2
-
5
-
-
1
-
-
-
1
-
6
-
-
-
-
-
-
-
-
2
-
-
-
-
1
1
2
-
-
-
-
-
-
-
-
-
2
2
-
-
-
1
-
-
1
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
657650
Moutaouakkil
Purification and partial chara ...
Pantoea agglomerans
Arch. Biochem. Biophys.
413
139-146
2003
-
1
-
-
-
-
5
2
-
-
1
-
-
1
-
-
1
-
-
-
-
1
5
1
1
1
-
-
1
1
-
1
-
-
5
-
1
-
1
-
-
-
5
5
-
2
-
-
1
-
-
-
-
1
-
-
-
1
5
1
1
1
-
-
1
1
-
-
-
-
-
-
-
-
657580
Blumel
Molecular cloning and characte ...
Xenophilus azovorans, Xenophilus azovorans KF46F / DSM 13620
Appl. Environ. Microbiol.
68
3948-3955
2002
-
1
1
-
-
-
-
-
-
-
3
2
-
6
-
-
1
-
-
-
1
-
4
1
-
-
-
-
-
-
-
3
-
-
-
-
1
1
3
-
-
-
-
-
-
-
-
-
3
2
-
-
-
1
-
-
1
-
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394314
Suzuki
Molecular cloning and characte ...
Bacillus sp. (in: Bacteria)
J. Biol. Chem.
276
9059-9065
2001
-
-
1
-
-
-
-
-
-
-
1
-
-
1
-
-
1
-
-
-
2
-
3
1
2
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
2
-
3
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
394313
Mazumder
-
Characteristics and purificati ...
Brevundimonas subvibrioides
J. Ind. Microbiol. Biotechnol.
23
476-483
1999
-
-
-
-
-
-
-
6
-
-
1
-
-
1
-
-
1
-
-
2
1
-
1
1
-
-
-
-
1
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
6
-
-
1
-
-
-
-
1
-
2
1
-
1
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
394312
Singh
Azo reductase activity of micr ...
Canis lupus familiaris, Capra hircus, Cavia porcellus, Cricetinae, Felis catus, Gallus gallus, Macaca mulatta, Mus musculus, Oryctolagus cuniculus, Ovis aries, Pigeon, Rattus norvegicus
Indian J. Exp. Biol.
36
99-103
1998
-
-
-
-
-
-
-
-
-
-
-
-
-
21
-
-
-
-
-
33
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
33
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394311
Singh
Comparative azo reductase acti ...
Rattus norvegicus
Indian J. Exp. Biol.
35
1016-1018
1997
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
1
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394310
Ghosh
Purification of two azoreducta ...
Escherichia coli
Indian J. Exp. Biol.
31
951-954
1993
1
-
-
-
-
-
-
2
-
-
3
-
-
1
-
-
1
-
-
-
8
-
4
1
1
-
-
-
1
-
-
4
-
-
-
1
-
-
4
-
-
-
-
-
-
2
-
-
3
-
-
-
-
1
-
-
8
-
4
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
394300
Rafii
Azoreductase activity of anaer ...
Anaerostipes hadrus, Bacteroides sp., Butyrivibrio sp., Clostridium clostridioforme, Clostridium paraputrificum, Clostridium perfringens, Clostridium sp., Eubacterium sp., Tyzzerella nexilis
Appl. Environ. Microbiol.
56
2146-2151
1990
-
-
-
-
-
-
-
-
9
-
-
-
-
9
9
-
-
-
-
-
-
-
17
-
-
-
-
-
-
-
-
9
-
-
-
-
-
-
9
-
-
-
-
-
-
-
9
-
-
-
-
9
-
-
-
-
-
-
17
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394299
Zimmermann
Comparison of two bacterial az ...
Pseudomonas sp., Pseudomonas sp. K24
Arch. Microbiol.
138
37-43
1984
-
-
-
-
-
-
1
6
-
-
2
2
-
3
-
-
1
-
-
-
2
-
10
1
1
-
-
-
2
-
-
2
-
-
-
-
-
-
2
-
-
-
-
1
-
6
-
-
2
2
-
-
-
1
-
-
2
-
10
1
1
-
-
-
2
-
-
-
-
-
-
-
-
-
394301
Moreno
Ca2+ and Mg2+-enhanced reducti ...
Rattus norvegicus
J. Biol. Chem.
259
14609-14616
1984
-
-
-
-
-
-
-
-
2
-
-
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394298
Zimmermann
Properties of purified Orange ...
Pseudomonas sp., Pseudomonas sp. KF46
Eur. J. Biochem.
129
197-203
1982
-
-
-
-
-
-
1
18
-
-
2
-
-
3
-
-
1
-
-
-
2
1
21
1
1
1
1
-
2
-
-
2
-
-
-
-
-
-
2
-
-
-
-
1
-
18
-
-
2
-
-
-
-
1
-
-
2
1
21
1
1
1
1
-
2
-
-
-
-
-
-
-
-
-
394302
Fujita
The stimulation of microsomal ...
Rattus norvegicus
Biochim. Biophys. Acta
719
178-189
1982
2
-
-
-
-
-
1
1
1
-
-
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
3
1
-
-
2
-
-
3
-
-
-
-
1
1
1
1
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394303
Mallett
A continuous spectrophotometri ...
Rattus norvegicus
Biochem. J.
201
589-595
1982
1
-
-
-
-
-
-
1
-
-
-
-
-
4
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
1
-
-
2
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394296
Huang
Rat liver cytosolic azoreducta ...
Rattus norvegicus
J. Biol. Chem.
254
3930-3934
1979
1
-
-
-
-
-
-
3
1
-
2
-
-
1
-
-
1
-
-
1
1
-
2
1
-
-
-
-
1
1
-
4
-
-
-
1
-
-
4
-
-
-
-
-
-
3
1
-
2
-
-
-
-
1
-
1
1
-
2
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
394297
Huang
Rat liver cytosolic azoreducta ...
Rattus norvegicus
J. Biol. Chem.
254
11223-11227
1979
-
-
-
-
-
-
1
-
-
1
-
-
-
1
-
-
-
-
-
1
1
-
7
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
1
2
-
-
1
-
-
-
-
-
-
-
1
1
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394304
Mallett
The apparent non-identity of c ...
Rattus norvegicus
Biochem. Soc. Trans.
6
1302-1305
1978
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
2
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394305
Fujita
Liver microsomal cytochromes P ...
Mus musculus
J. Biol. Chem.
253
4512-4513
1978
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394295
Matsudomi
-
Purification and some properti ...
Bacillus cereus, Bacillus cereus T-105
Agric. Biol. Chem.
41
2323-2329
1977
1
-
-
-
-
-
7
-
1
1
-
-
-
2
-
-
1
-
-
-
1
-
4
-
1
1
2
-
1
1
1
5
-
-
-
1
-
-
5
-
-
-
-
7
-
-
1
1
-
-
-
-
-
1
-
-
1
-
4
-
1
1
2
-
1
1
1
-
-
-
-
-
-
-
394306
Mallett
A continuous assay for hepatic ...
Rattus norvegicus
Biochem. Soc. Trans.
5
1522-1524
1977
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394307
Smith
1,2-Dimethyl-4-(p-carboxypheny ...
Canis lupus familiaris, Cavia porcellus, Gallus gallus, Microtus pennsylvanicus, Rattus norvegicus
Anal. Biochem.
31
315-320
1969
3
-
-
-
-
-
-
1
-
-
-
-
-
5
-
-
-
-
-
5
5
-
10
-
-
-
-
-
-
-
-
1
-
-
-
3
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
5
5
-
10
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394308
Daniel
A soluble aerobic reduced nico ...
Rattus norvegicus
Biochem. J.
11
19P-20P
1969
-
-
-
-
-
-
1
-
-
1
-
-
-
1
-
-
1
-
-
1
-
-
2
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
3
-
-
-
-
1
-
-
-
1
-
-
-
-
-
1
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394309
Ketterer
-
The effect of 4-dimethylaminoa ...
Rattus norvegicus
Biochem. J.
107
15P-16P
1968
-
-
-
-
-
-
2
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-