Inhibitors | Comment | Organism | Structure |
---|---|---|---|
AMP | weak | Escherichia coli | |
AMP | weak | Klebsiella aerogenes | |
AMP | weak | Salmonella enterica subsp. enterica serovar Typhimurium | |
ATP | - |
Escherichia coli | |
ATP | - |
Klebsiella aerogenes | |
ATP | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
IMP | - |
Escherichia coli | |
IMP | - |
Klebsiella aerogenes | |
IMP | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
additional information | not inhibited by KCN | Escherichia coli | |
additional information | not inhibited by KCN | Klebsiella aerogenes | |
additional information | not inhibited by KCN | Salmonella enterica subsp. enterica serovar Typhimurium |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.096 | - |
GMP | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
0.096 | - |
GMP | - |
Escherichia coli | |
0.096 | - |
GMP | - |
Klebsiella aerogenes |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | no requirement for monovalent or divalent cations | Salmonella enterica subsp. enterica serovar Typhimurium | |
additional information | no requirement for monovalent or divalent cations | Escherichia coli | |
additional information | no requirement for monovalent or divalent cations | Klebsiella aerogenes |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Klebsiella aerogenes | - |
- |
- |
Salmonella enterica subsp. enterica serovar Typhimurium | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
72.4 units/mg, 1 unit is defined as the amount of enzyme producing a decrease in absorbancy at 340 nm of 0.1 per min | Salmonella enterica subsp. enterica serovar Typhimurium |
additional information | - |
72.4 units/mg, 1 unit is defined as the amount of enzyme producing a decrease in absorbancy at 340 nm of 0.1 per min | Escherichia coli |
additional information | - |
72.4 units/mg, 1 unit is defined as the amount of enzyme producing a decrease in absorbancy at 340 nm of 0.1 per min | Klebsiella aerogenes |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADPH + guanosine 5'-phosphate | specific for GMP | Salmonella enterica subsp. enterica serovar Typhimurium | NADP+ + inosine 5'-phosphate + NH3 | - |
ir | |
NADPH + guanosine 5'-phosphate | specific for GMP | Escherichia coli | NADP+ + inosine 5'-phosphate + NH3 | - |
ir | |
NADPH + guanosine 5'-phosphate | specific for GMP | Klebsiella aerogenes | NADP+ + inosine 5'-phosphate + NH3 | - |
ir |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | 8.2 | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
7.5 | 8.2 | - |
Escherichia coli |
7.5 | 8.2 | - |
Klebsiella aerogenes |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | specific for | Salmonella enterica subsp. enterica serovar Typhimurium | |
NADPH | specific for | Escherichia coli | |
NADPH | specific for | Klebsiella aerogenes |