Literature summary for 1.7.1.9 extracted from

Stanley, J.S.; York, J.L.; Benson, a.M.
Nitroreductases and glutathione transferases that act on 4-nitroquinoline 1-oxide and their differential induction by butylated hydroxyanisole in mice (1992), Cancer Res., 52, 58-63.

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Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	not inhibited by dicoumarol	Mus musculus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.015	-	4-Nitroquinoline N-oxide	-	Mus musculus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
200000	-	-	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4-nitroquinoline N-oxide + NAD(P)H + H+	strong preference for NADH	Mus musculus	4-(hydroxyamino)quinoline N-oxide + NAD(P)+ + H2O	-	?

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Release 2023.1 (January 2023)