Literature summary for 1.7.3.3 extracted from

Zhou, Z.; Zhao, H.; Zhang, L.; Xie, Q.; Liu, Q.; Tong, M.; Yu, X.; Xiong, S.
Soluble expression of bioactive recombinant porcine-human chimeric uricase mutant employing MBP-SUMO fusion system (2022), Protein Expr. Purif., 189, 105978 .

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli by combination of small ubiquitin-related modifier protein and maltose-binding protein to achieve the soluble expression of chimeric enzyme	Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
urate + O2 + H2O	Sus scrofa	-	5-hydroxyisourate + H2O2	-	?

Organism

Organism	UniProt	Comment	Textmining
Sus scrofa	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
urate + O2 + H2O	-	Sus scrofa	5-hydroxyisourate + H2O2	-	?

Synonyms

Synonyms	Comment	Organism
dHU-wPU	humanized chimeric uricase based on wild porcine uricase (wPU), which can effectively reduce the limitation of potential immunogenicity with a high homology (92.76%) to deduced human uricase (dHU)	Sus scrofa
uricase	-	Sus scrofa

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Release 2023.1 (January 2023)