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Literature summary for 1.8.1.5 extracted from

  • Streit, B.R.; Mattice, J.R.; Prussia, G.A.; Peters, J.W.; DuBois, J.L.
    The reactive form of a C-S bond-cleaving, CO2-fixing flavoenzyme (2019), J. Biol. Chem., 294, 5137-5145 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.8.1.5

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3)pLysS cells Xanthobacter autotrophicus

Inhibitors

Inhibitors Comment Organism Structure
bromoethanesulfonate
-
 Xanthobacter autotrophicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2-oxopropyl-coenzyme M + CO2 + NADPH Xanthobacter autotrophicus
-
 coenzyme M + acetoacetate + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Xanthobacter autotrophicus Q56839
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA resin column chromatography, and DEAE-Sepharose column chromatography Xanthobacter autotrophicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-oxopropyl-coenzyme M + CO2 + NADPH
-
 Xanthobacter autotrophicus coenzyme M + acetoacetate + NADP+
-
 ?

Subunits

Subunits Comment Organism
homodimer x-ray crystallography Xanthobacter autotrophicus

Synonyms

Synonyms Comment Organism
2-KPCC
-
 Xanthobacter autotrophicus
NADPH:2-ketopropyl-coenzyme M oxidoreductase/carboxylase
-
 Xanthobacter autotrophicus

Cofactor

Cofactor Comment Organism Structure
FAD
-
 Xanthobacter autotrophicus
NADPH
-
 Xanthobacter autotrophicus