Activating Compound | Comment | Organism | Structure |
---|---|---|---|
FAD analogues | properties of glutathione reductase reconstituted with FAD analogues | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
binding structure of diverse FAD analogues to the apoenzyme | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
2 glutathione + NADP+ = glutathione disulfide + NADPH + H+ | mechanism | Homo sapiens | |
2 glutathione + NADP+ = glutathione disulfide + NADPH + H+ | cofactor binding of glutathione reductase with FAD analogues, reconstitution | Homo sapiens |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
relative activity and reaction velocity with diverse FAD analogues | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GSSG + NADPH | - |
Homo sapiens | glutathione + NADP+ | - |
r | |
additional information | active with diverse FAD analogues, dependent on orientation of the cofactor | Homo sapiens | ? | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | properties of glutathione reductase reconstituted with FAD analogues | Homo sapiens | |
FAD | FAD enzyme | Homo sapiens | |
FAD | activity with diverse FAD analogues | Homo sapiens | |
NADPH | - |
Homo sapiens |