Inhibitors | Comment | Organism | Structure |
---|---|---|---|
15-deoxy-D-12,14-PGJ2 | 0.06 mM, IC50: 0.00036 mM | Rattus norvegicus | |
3,4-estronequinone | 0.032 mM, IC50: 0.02 mM | Rattus norvegicus | |
4-hydroxynonenal | 0.06 mM, IC50: 0.012 mM | Rattus norvegicus | |
leukotriene A4 methyl ester | 0.06 mM, IC50: 0.513 mM | Rattus norvegicus | |
Prostaglandin A2 | 0.06 mM, IC50: 0.068 mM | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
DE52 column chromatography | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
thioredoxin + NADP+ | - |
Rattus norvegicus | thioredoxin disulfide + NADPH | - |
? |
Subunits | Comment | Organism |
---|---|---|
homodimer | - |
Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
thioredoxin reductase | - |
Rattus norvegicus |
TrxR | - |
Rattus norvegicus |
TrxR1 | - |
Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000024 | - |
15-deoxy-D-12,14-PGJ2 | - |
Rattus norvegicus | |
0.0008 | - |
4-hydroxynonenal | - |
Rattus norvegicus | |
0.001 | - |
3,4-estronequinone | - |
Rattus norvegicus | |
0.0045 | - |
Prostaglandin A2 | - |
Rattus norvegicus | |
0.033 | - |
leukotriene A4 methyl ester | - |
Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00036 | - |
0.06 mM, IC50: 0.00036 mM | Rattus norvegicus | 15-deoxy-D-12,14-PGJ2 | |
0.012 | - |
0.06 mM, IC50: 0.012 mM | Rattus norvegicus | 4-hydroxynonenal | |
0.02 | - |
0.032 mM, IC50: 0.02 mM | Rattus norvegicus | 3,4-estronequinone | |
0.068 | - |
0.06 mM, IC50: 0.068 mM | Rattus norvegicus | Prostaglandin A2 | |
0.513 | - |
0.06 mM, IC50: 0.513 mM | Rattus norvegicus | leukotriene A4 methyl ester |