Any feedback?
Literature summary for 1.8.1.9 extracted from
- Characterization of protein targets of mammalian thioredoxin reductases (2010), Methods Enzymol., 474, 245-254.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21(DE3) cells | Mus musculus |
| expressed in Escherichia coli BL21(DE3) cells | Rattus norvegicus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | isoform TR1 | Mus musculus | 5829 | - |
| cytosol | isoform TR1 | Homo sapiens | 5829 | - |
| cytosol | isoform TR1 | Rattus norvegicus | 5829 | - |
| mitochondrion | isoform TR2 | Mus musculus | 5739 | - |
| mitochondrion | isoform TR2 | Homo sapiens | 5739 | - |
| mitochondrion | isoform TR2 | Rattus norvegicus | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| HisBind HiTrap metal-affinity column chromatography, 2',5'-ADP-Sepharose column chromatography, and CNBr-activated Sepharose column chromatography | Mus musculus |
| HisBind HiTrap metal-affinity column chromatography, 2',5'-ADP-Sepharose column chromatography, and CNBr-activated Sepharose column chromatography | Homo sapiens |
| HisBind HiTrap metal-affinity column chromatography, 2',5'-ADP-Sepharose column chromatography, and CNBr-activated Sepharose column chromatography | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Mus musculus | - |
| liver | - |
Rattus norvegicus | - |
| testis | isoform TR3 | Mus musculus | - |
| testis | isoform TR3 | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| thioredoxin disulfide + NADPH + H+ | - |
Mus musculus | thioredoxin + NADP+ | - |
? |  |
| thioredoxin disulfide + NADPH + H+ | - |
Homo sapiens | thioredoxin + NADP+ | - |
? | |
| thioredoxin disulfide + NADPH + H+ | - |
Rattus norvegicus | thioredoxin + NADP+ | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| thioredoxin reductase | - |
Mus musculus |
| thioredoxin reductase | - |
Homo sapiens |
| thioredoxin reductase | - |
Rattus norvegicus |
| TR1 | isoform | Mus musculus |
| TR1 | isoform | Homo sapiens |
| TR1 | isoform | Rattus norvegicus |
| TR2 | isoform | Mus musculus |
| TR2 | isoform | Homo sapiens |
| TR2 | isoform | Rattus norvegicus |
| TR3 | isoform | Mus musculus |
| TR3 | isoform | Rattus norvegicus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FAD | - |
Mus musculus | |
| FAD | - |
Homo sapiens | |
| FAD | - |
Rattus norvegicus | |
| NADPH | - |
Mus musculus | |
| NADPH | - |
Homo sapiens | |
| NADPH | - |
Rattus norvegicus | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
