Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | the enzyme is not inhibited by dimedone even at 150fold excess | Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.134 | - |
methaneseleninic acid | at pH 6.1 and 37°C | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Mus musculus | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
thioredoxin disulfide + NADPH + H+ | Mus musculus | - |
thioredoxin + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Oxidation Stability | Organism |
---|---|
the enzyme strongly resists inactivation by 50 mM H2O2 | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
methaneseleninic acid + NADP+ | - |
Mus musculus | ? + NADPH + H+ | - |
? | |
thioredoxin disulfide + NADPH + H+ | - |
Mus musculus | thioredoxin + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TR1 | - |
Mus musculus |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
16.05 | - |
methaneseleninic acid | at pH 6.1 and 37°C | Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.1 | - |
- |
Mus musculus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6 | 6.5 | around 60% activity at pH 6.0 and 6.5 | Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Mus musculus | |
NADPH | - |
Mus musculus |