KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.18 | - |
ferricyanide | S0.5 value, pH 4.0, 42°C | Campylobacter jejuni | |
0.2 | - |
thiosulfate | pH 4.0, 42°C | Campylobacter jejuni |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Campylobacter jejuni | - |
bifunctional tetrathionate reductase/thiosulfate dehydrogenase | - |
Campylobacter jejuni NCTC 11828 | - |
bifunctional tetrathionate reductase/thiosulfate dehydrogenase | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 thiosulfate + 2 ferricyanide | stoichiometric ratio of conversion is of 1 mole tetrathionate to 2 mol initial thiosulfate. Enzyme can couple thiosulfate oxidation to electron transport to oxygen | Campylobacter jejuni | tetrathionate + 2 ferrocyanide | - |
? | |
2 thiosulfate + 2 ferricyanide | stoichiometric ratio of conversion is of 1 mole tetrathionate to 2 mol initial thiosulfate. Enzyme can couple thiosulfate oxidation to electron transport to oxygen | Campylobacter jejuni NCTC 11828 | tetrathionate + 2 ferrocyanide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
C8J_0815 | locus name | Campylobacter jejuni |
TsdA | - |
Campylobacter jejuni |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
42 | - |
- |
Campylobacter jejuni |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
604 | - |
thiosulfate | pH 4.0, 42°C | Campylobacter jejuni |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
4 | - |
substrate ferricyanide | Campylobacter jejuni |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | sequence shows two Cys-X2-Cys-His heme c-binding motifs | Campylobacter jejuni |
General Information | Comment | Organism |
---|---|---|
physiological function | growth of the microaerophilic mucosal pathogen Campylobacter jejuni under oxygen-limited conditions is stimulated by tetrathionate. A tsdA null mutant still slowly reduces, but can not grow on, tetrathionate under oxygen limitation, lacks thiosulfate-dependent respiration and fails to convert thiosulfate to tetrathionate microaerobically. Physiological role for Campylobacter jejuni TsdA is a tetrathionate reductase | Campylobacter jejuni |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
302 | - |
thiosulfate | pH 4.0, 42°C | Campylobacter jejuni |