Literature summary for 1.8.3.2 extracted from

Morel, C.; Adami, P.; Musard, J.F.; Duval, D.; Radom, J.; Jouvenot, M.
Involvement of sulfhydryl oxidase QSOX1 in the protection of cells against oxidative stress-induced apoptosis (2007), Exp. Cell Res., 313, 3971-3982.

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Activating Compound

Activating Compound	Comment	Organism	Structure
H2O2	high concentrations of H2O2, inducing apoptosis, cause an increase of QSOX1 mRNA and protein	Rattus norvegicus
staurosporine aglycone	-	Rattus norvegicus

Application

Application	Comment	Organism
medicine	protective role of QSOX1 against apoptosis	Rattus norvegicus
medicine	protective role of QSOX1 against apoptosis. QSOX1 short transcript overexpression slows down proliferation and protects cells from oxidative stress-induced cell death	Cavia porcellus

Cloned(Commentary)

Cloned (Comment)	Organism
overexpression in MCF-7 cell lines	Cavia porcellus

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Fe3+	-	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Cavia porcellus	O08841	-	-
Rattus norvegicus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Cavia porcellus

Source Tissue

Source Tissue	Comment	Organism	Textmining
PC-12 cell	-	Rattus norvegicus	-

Synonyms

Synonyms	Comment	Organism
QSOx1	-	Rattus norvegicus
QSOx1	-	Cavia porcellus
sulfhydryl oxidase	-	Rattus norvegicus
sulfhydryl oxidase	-	Cavia porcellus

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Release 2023.1 (January 2023)