Literature summary for 1.8.3.2 extracted from

Franca, K.C.; Martinez, P.A.; Prado, M.L.; Lo, S.M.; Borges, B.E.; Zanata, S.M.; San Martin, A.; Nakao, L.S.
Quiescin/sulfhydryl oxidase 1b (QSOX1b) induces migration and proliferation of vascular smooth muscle cells by distinct redox pathways (2020), Arch. Biochem. Biophys., 679, 108220 .

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Protein Variants

Protein Variants	Comment	Organism
C452S	inactive enzyme	Rattus norvegicus
C455S	inactive enzyme	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
extracellular	-	Rattus norvegicus	-	-

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Synonyms

Synonyms	Comment	Organism
QSOX	-	Rattus norvegicus
QSOX1b	-	Rattus norvegicus
quiescin/sulfhydryl oxidase 1b	-	Rattus norvegicus

General Information

General Information	Comment	Organism
physiological function	the extracellular enzyme (QSOX1b) transduces migratory and mitogenic responses in primary vascular smooth muscle cells by distinct pathways. The migratory pathway is triggered by active QSOX1b and depends on hydrogen peroxide from Nox1-derived superoxide. The enzyme has a role in neointima formation in balloon-injured rat carotid	Rattus norvegicus

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Release 2023.1 (January 2023)