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Literature summary for 1.8.3.7 extracted from

  • Mariappan, M.; Preusser-Kunze, A.; Balleininger, M.; Eiselt, N.; Schmidt, B.; Gande, S.L.; Wenzel, D.; Dierks, T.; von Figura, K.
    Expression, localization, structural, and functional characterization of pFGE, the paralog of the Calpha-formylglycine-generating enzyme (2005), J. Biol. Chem., 280, 15173-15179 .
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
a [sulfatase]-L-cysteine + O2 + a thiol Homo sapiens
-
 a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q8NBK3
-
-

Source Tissue

Source Tissue Comment Organism Textmining
skin fibroblast
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
a [sulfatase]-L-cysteine + O2 + a thiol
-
 Homo sapiens a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H2O
-
 ?

Subunits

Subunits Comment Organism
? x * 32000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
Calpha-formylglycine-generating enzyme
-
 Homo sapiens
FGE
-
 Homo sapiens
SUMF1
-
 Homo sapiens

General Information

General Information Comment Organism
metabolism enzyme overexpression stimulates the generation of catalytically active sulfatases Homo sapiens