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BRENDA support

Literature summary for 1.8.4.11 extracted from

  • Benoit, S.L.; Bayyareddy, K.; Mahawar, M.; Sharp, J.S.; Maier, R.J.
    Alkyl hydroperoxide reductase repair by Helicobacter pylori methionine sulfoxide reductase (2013), J. Bacteriol., 195, 5396-5401 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Helicobacter pylori
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
methionine sulfoxide in alkyl hydroperoxide reductase C + thioredoxin
-
Helicobacter pylori methionine in alkyl hydroperoxide reductase C + thioredoxin disulfide + H2O
-
?

Cofactor

Cofactor Comment Organism Structure
thioredoxin
-
Helicobacter pylori

General Information

General Information Comment Organism
physiological function a strain lacking Msr activtiy is more sensitive to HOCl-mediated killing than the parent Helicobacter pylori