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Literature summary for 1.8.4.2 extracted from

  • Varandani, P.T.; Nafz, M.A.
    Interaction of glutathione-insulin transhydrogenase (disulfide interchange enzyme) with phospholipids (1976), Biochim. Biophys. Acta, 438, 358-369.
    View publication on PubMed
Search for more literature for 1.8.4.2

Activating Compound

Activating Compound Comment Organism Structure
Phospholipids slight activation by all phospholipids tested except for phosphatidic acid and phosphatidylserine, highest activation by phosphatidylethanolamine Rattus norvegicus
Phospholipids slight activation by all phospholipids tested except for phosphatidic acid and phosphatidylserine, highest activation by phosphatidylethanolamine Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
lysophosphatidylcholine
-
 Bos taurus
lysophosphatidylcholine
-
 Rattus norvegicus
phosphatidic acid
-
 Bos taurus
phosphatidic acid
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-
liver
-
 Bos taurus
-
pancreas
-
 Rattus norvegicus
-
pancreas
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GSH + insulin
-
 Bos taurus GSSG + reduced insulin chain A and B
-
 ?
GSH + protein disulfide
-
 Rattus norvegicus GSSG + protein-dithiol
-
 ?
GSH + protein disulfide
-
 Bos taurus GSSG + protein-dithiol
-
 ?