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Literature summary for 1.8.5.9 extracted from

  • Hayashi, S.; Mitsuko, A.; Kimoto, M.; Furukawa, S.; Nakazawa, T.
    The dsbA-dsbB disulfide bond formation system of Burkholderia cepacia is involved in the production of protease and alkaline phosphatase, motility, metal resistance, and multi-drug resistance (2000), Microbiol. Immunol., 44, 41-50 .
    View publication on PubMed
Search for more literature for 1.8.5.9

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Burkholderia cepacia 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
[DsbA protein] with reduced L-cysteine residues + a quinone Burkholderia cepacia overall reaction [DsbA protein] carrying a disulfide bond + a quinol
-
 ?
[DsbA protein] with reduced L-cysteine residues + a quinone Burkholderia cepacia KF1 overall reaction [DsbA protein] carrying a disulfide bond + a quinol
-
 ?

Organism

Organism UniProt Comment Textmining
Burkholderia cepacia
-
-
-
Burkholderia cepacia KF1
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
[DsbA protein] with reduced L-cysteine residues + a quinone overall reaction Burkholderia cepacia [DsbA protein] carrying a disulfide bond + a quinol
-
 ?
[DsbA protein] with reduced L-cysteine residues + a quinone overall reaction Burkholderia cepacia KF1 [DsbA protein] carrying a disulfide bond + a quinol
-
 ?

Synonyms

Synonyms Comment Organism
disulfide bond oxidoreductase B
-
 Burkholderia cepacia
DsbB
-
 Burkholderia cepacia

General Information

General Information Comment Organism
malfunction mutation in the DsbA-enzyme system results in an increase in sensitivity to Cd2+ and Zn2+ as well as a variety of antibiotics including beta-lactams, kanamycin, erythromycin, novobiocin, ofloxacin and sodium dodecyl sulfate Burkholderia cepacia