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Literature summary for 1.8.99.5 extracted from

  • Nguyen, P.T.; Toh-E, A.; Nguyen, N.H.; Imanishi-Shimizu, Y.; Watanabe, A.; Kamei, K.; Shimizu, K.
    Identification and characterization of a sulfite reductase gene and new insights regarding the sulfur-containing amino acid metabolism in the basidiomycetous yeast Cryptococcus neoformans (2021), Curr. Genet., 67, 115-128 .
    View publication on PubMed
Search for more literature for 1.8.99.5

Cloned(Commentary)

Cloned (Comment) Organism
gene MET5, DNA and amino acid sequence determination and analysis Cryptococcus neoformans var. neoformans

Protein Variants

Protein Variants Comment Organism
additional information construction of large scale amounts of random T-DNA-inserted mutants, identification of a knockout mutant DELTAMet5. The DELTAMet5 mutant grows on sulfide but not on either sulfate or sulfite, it also grows well on Cys and homocysteine, but much slower in the presence of Met Cryptococcus neoformans var. neoformans

Organism

Organism UniProt Comment Textmining
Cryptococcus neoformans var. neoformans Q5K8J1 Filobasidiella neoformans, serotype D
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Cryptococcus neoformans var. neoformans ATCC MYA-565 Q5K8J1 Filobasidiella neoformans, serotype D
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Cryptococcus neoformans var. neoformans JEC21 Q5K8J1 Filobasidiella neoformans, serotype D
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme catalyzes the reduction of sulfite to sulfide Cryptococcus neoformans var. neoformans ?
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-
additional information the enzyme catalyzes the reduction of sulfite to sulfide Cryptococcus neoformans var. neoformans ATCC MYA-565 ?
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additional information the enzyme catalyzes the reduction of sulfite to sulfide Cryptococcus neoformans var. neoformans JEC21 ?
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-

Subunits

Subunits Comment Organism
heterodimer
-
 Cryptococcus neoformans var. neoformans

Synonyms

Synonyms Comment Organism
CNL05500
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 Cryptococcus neoformans var. neoformans
MET5
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 Cryptococcus neoformans var. neoformans
sulfite reductase
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 Cryptococcus neoformans var. neoformans

General Information

General Information Comment Organism
metabolism the enzyme encoded by MET5 is involved in the sulfur metabolic pathway in the sulfur assimilation of Cryptococcus neoformans, overview. Sulfate is used by the active MET3, MET14, MET5, and MET10 genes in the sulfate assimilation pathway Cryptococcus neoformans var. neoformans
physiological function the sulfite reductase MET5 gene confers Cys auxotrophy Cryptococcus neoformans var. neoformans