Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
TK-6 cell | B lymphoblast cell line containing wild-type p53. The interaction between p53 and DNMT1 controls DNA methylation of the p16ink4A promoter that consequently reduces the level of the p16ink4A | Homo sapiens | - |
WTK-1 cell | B lymphoblast cell line with mutant p53. Mutant p53 loses its ability to suppress DNMT1 expression, and thus enhances methylation levels of the p16ink4A promoter and subsequently down-regulates p16ink4A protein | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
DNA (cytosine-5)-methyltransferase 1 | - |
Homo sapiens |
Dnmt1 | - |
Homo sapiens |