Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adenocarcinoma cell | cell line SKGT4 | Homo sapiens | - |
squamous cell carcinoma cell | cell lines TE-3 and TE-12 | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
DNA (cytosine-5-)-methyltransferase 3A | - |
Homo sapiens |
Dnmt3a | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | BPDE recruits DNMT3A to methylate the RAR-beta2 gene promoter and thus silence its gene expression, which in turn, may contribute to the malignant transformation of esophageal epithelial cells | Homo sapiens |