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Literature summary for 2.1.1.45 extracted from
- Spectroscopic analysis of folate binding to thymidylate synthase active site (2009), Spectrosc. Lett., 42, 142-146.
No PubMed abstract available
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| K48Q | the mutant is impaired in folate binding | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5,10-methylenetetrahydrofolate + dUMP | - |
Escherichia coli | dihydrofolate + dTMP | - |
? |  |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| N5,N10-methylenetetrahydrofolate | - |
Escherichia coli | |
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Release 2023.1 (January 2023)
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