Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Rattus norvegicus | |
iodoacetic acid | - |
Rattus norvegicus | |
Mg2+ | inhibition above 2 mM; required for activity | Rattus norvegicus | |
N-ethylmaleimide | - |
Rattus norvegicus | |
p-chloromercuribenzoate | - |
Rattus norvegicus | |
S-adenosyl-L-homocysteine | - |
Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Rattus norvegicus | |
Mg2+ | inhibition above 2 mM | Rattus norvegicus | |
Mg2+ | below 2 mM | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
23000 | - |
x * 23000, SDS-PAGE | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | primary role in extraneuronal inactivation of endogenous catecholamines and in the further metabolism of oxidized catecholamine metabolites | ? | - |
? | |
S-adenosyl-L-methionine + a catechol | Rattus norvegicus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Rattus norvegicus |
Storage Stability | Organism |
---|---|
-4°C, stable for several weeks | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | not: monophenols | Rattus norvegicus | ? | - |
? | |
additional information | strict requirement for S-adenosyl-L-methionine as methyl donor and a catechol as acceptor substrate | Rattus norvegicus | ? | - |
? | |
additional information | primary role in extraneuronal inactivation of endogenous catecholamines and in the further metabolism of oxidized catecholamine metabolites | Rattus norvegicus | ? | - |
? | |
S-adenosyl-L-methionine + a catechol | - |
Rattus norvegicus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 23000, SDS-PAGE | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.3 | 8.2 | - |
Rattus norvegicus |