Literature summary for 2.1.1.6 extracted from

Rhee, J.; Myung Un, C.
Rat liver catechol-O-methyltransferase: Purification and general properties (1988), Hanguk Saenghwahakhoe Chi, 21, 60-67.

No PubMed abstract available

Search for more literature for 2.1.1.6

Inhibitors

Inhibitors	Comment	Organism	Structure
high ionic strength	-	Rattus norvegicus
iodoacetic acid	-	Rattus norvegicus
Mg2+	required for activity	Rattus norvegicus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0038	-	p-nitrocatechol	-	Rattus norvegicus
0.283	-	S-adenosyl-L-methionine	-	Rattus norvegicus

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	required	Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
25700	-	1 * 25700, liver, SDS-PAGE	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Rattus norvegicus

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
p-nitrocatechol + S-adenosyl-L-methionine	-	Rattus norvegicus	S-adenosyl-L-homocysteine + ?	-	?

Subunits

Subunits	Comment	Organism
monomer	1 * 25700, liver, SDS-PAGE	Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
50	-	-	Rattus norvegicus

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7.8	-	-	Rattus norvegicus

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Release 2023.1 (January 2023)