Cloned (Comment) | Organism |
---|---|
isolation and sequencing of cDNA clones encoding bifunctional enzyme with formiminotransferase and cyclodeaminase activity, EC 2.1.2.5 and EC 4.3.1.4, cDNA encodes an amino acid sequence of 541 residues, expression in Escherichia coli | Sus scrofa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
58926 | - |
8 * 58926, recombinant bifunctional enzyme with formiminotransferase and cyclodeaminase activity, EC 2.1.2.5 and EC 4.3.1.4, calculated from cDNA sequence | Sus scrofa |
480000 | - |
approximately, native octameric bifunctional enzyme with formiminotransferase and cyclodeaminase activity, EC 2.1.2.5 and EC 4.3.1.4 | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | P53603 | - |
- |
Purification (Comment) | Organism |
---|---|
purification of recombinant bifunctional enzyme with formiminotransferase and cyclodeaminase activity, EC 2.1.2.5 and EC 4.3.1.4, expressed in Escherichia coli | Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
39 | 41 | recombinant enzyme, expressed in Escherichia coli | Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | FTCD: bifunctional enzyme with 5-formiminotetrahydrofolate:L-glutamate N-formiminotransferase activity, EC 2.1.2.5, and formiminotetrahydrofolate cyclodeaminase activity, EC 4.3.1.4 | Sus scrofa | ? | - |
? | |
tetrahydrofolate + N-formimino-L-glutamate | - |
Sus scrofa | 5-formiminotetrahydrofolate + L-glutamate | - |
? |
Subunits | Comment | Organism |
---|---|---|
octamer | 8 * 58926, recombinant bifunctional enzyme with formiminotransferase and cyclodeaminase activity, EC 2.1.2.5 and EC 4.3.1.4, calculated from cDNA sequence | Sus scrofa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
tetrahydrofolate | folate-dependent enzyme | Sus scrofa |