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Literature summary for 2.1.3.1 extracted from
- Effects of rapeseed oil on activity of methylmalonyl-CoA carboxyltransferase in culture of Streptomyces fradiae (1998), Biosci. Biotechnol. Biochem., 62, 902-906.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | industrial antibiotic production | Streptomyces fradiae |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Streptomyces fradiae | enzyme involved in the biosynthesis of the tylosin | ? | - |
? |  |
| additional information | Streptomyces fradiae T1558 | enzyme involved in the biosynthesis of the tylosin | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Streptomyces fradiae | - |
- |
- |
| Streptomyces fradiae T1558 | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
specific activity depends on the carbon source and increases during culture time | Streptomyces fradiae |
| 0.075 | - |
carbon source: glucose | Streptomyces fradiae |
| 0.15 | - |
carbon source: starch | Streptomyces fradiae |
| 0.19 | - |
carbon source: rapeseed oil | Streptomyces fradiae |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | enzyme catalyses the formation of the precursor of tylosin, protylonoide | Streptomyces fradiae | ? | - |
? | |
| additional information | enzyme involved in the biosynthesis of the tylosin | Streptomyces fradiae | ? | - |
? | |
| additional information | enzyme catalyses the formation of the precursor of tylosin, protylonoide | Streptomyces fradiae T1558 | ? | - |
? | |
| additional information | enzyme involved in the biosynthesis of the tylosin | Streptomyces fradiae T1558 | ? | - |
? | |
| propionyl-CoA + oxaloacetate | - |
Streptomyces fradiae | (S)-methylmalonyl-CoA + pyruvate | - |
? | |
| propionyl-CoA + oxaloacetate | - |
Streptomyces fradiae T1558 | (S)-methylmalonyl-CoA + pyruvate | - |
? | |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 7.5 | assay at | Streptomyces fradiae |
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