Activating Compound | Comment | Organism | Structure |
---|---|---|---|
L-malate | activation in presence of excess carbamoyl phosphate and limiting L-aspartate | Escherichia coli | |
mesotartrate | activation in presence of excess carbamoyl phosphate and limiting L-aspartate | Escherichia coli | |
succinate | activation in presence of excess carbamoyl phosphate and limiting L-aspartate | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,2-dimethylsuccinate | - |
Escherichia coli | |
acetate | - |
Escherichia coli | |
Cl- | - |
Escherichia coli | |
fumarate | - |
Escherichia coli | |
L-malate | - |
Escherichia coli | |
Maleate | - |
Escherichia coli | |
mesotartrate | - |
Escherichia coli | |
succinate | - |
Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
carbamoylphosphate + L-aspartate | Escherichia coli | - |
phosphate + N-carbamoyl-L-aspartate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
carbamoyl phosphate + L-aspartate | - |
Escherichia coli | phosphate + N-carbamoyl-L-aspartate | - |
? | |
carbamoylphosphate + L-aspartate | - |
Escherichia coli | phosphate + N-carbamoyl-L-aspartate | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.17 | - |
Maleate | inhibition of catalytic subunits, C3 | Escherichia coli | |
0.7 | - |
mesotartrate | inhibition of catalytic subunits, C3 | Escherichia coli | |
1.1 | - |
chloride | inhibition of catalytic subunits, C3 | Escherichia coli | |
2.2 | - |
2,2-dimethylsuccinate | inhibition of catalytic subunits, C3 | Escherichia coli | |
3.5 | - |
succinate | inhibition of catalytic subunits, C3 | Escherichia coli | |
5.3 | - |
fumarate | inhibition of catalytic subunits, C3 | Escherichia coli |