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Literature summary for 2.1.4.2 extracted from

  • Walker, J.B.
    Biosynthesis of the monoguanidinated inositol moiety of bluensomycin, a possible evolutionary precursor of streptomycin (1974), J. Biol. Chem., 249, 2397-2404.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate Streptomyces hygroscopicus biosynthesis of streptomycin L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate
-
?

Organism

Organism UniProt Comment Textmining
Streptomyces hygroscopicus
-
forma glebosus, ATCC 14607
-

Source Tissue

Source Tissue Comment Organism Textmining
mycelium
-
Streptomyces hygroscopicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
arginine + 1-D-1,3-diamino-1,2,3-trideoxy-scyllo-inositol 6-phosphate
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Streptomyces hygroscopicus ornithine + ?
-
?
arginine + 1-D-1,3-diamino-1,3-dideoxy-scyllo-inositol 6-phosphate
-
Streptomyces hygroscopicus ornithine + ?
-
?
arginine + 1-D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol 6-phosphate
-
Streptomyces hygroscopicus ornithine + ?
-
?
arginine + 1-D-1-O-carbamoyl-3-amino-3-deoxy-scyllo-inositol 6-phosphate
-
Streptomyces hygroscopicus ornithine + ?
-
?
arginine + NH2OH
-
Streptomyces hygroscopicus ornithine + ?
-
?
L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate biosynthesis of streptomycin Streptomyces hygroscopicus L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate
-
?
L-arginine + 1-amino-1-deoxy-scyllo-inositol-4-phosphate
-
Streptomyces hygroscopicus L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate
-
?