Literature summary for 2.2.1.6 extracted from

Yang, J.H.; Kim, S.S.
Purification and characterization of the valine sensitive acetolactate synthase from Serratia marcescens ATCC 25419 (1993), Biochim. Biophys. Acta, 1157, 178-184.

Search for more literature for 2.2.1.6

Inhibitors

Inhibitors	Comment	Organism	Structure
Ile	1 mM, 50% inhibition	Serratia marcescens
Leu	1 mM, 50% inhibition	Serratia marcescens
Val	0.1 mM, 50% inhibition	Serratia marcescens

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	required	Serratia marcescens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
178000	-	non-denaturing PAGE	Serratia marcescens
204000	-	gel filtration	Serratia marcescens

Organism

Organism	UniProt	Comment	Textmining
Serratia marcescens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Serratia marcescens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
pyruvate	-	Serratia marcescens	2-acetolactate + CO2	-	?
pyruvate + 2-oxobutanoate	no activity	Serratia marcescens	acetohydroxybutanoate	-	?

Temperature Stability [°C]

Temperature Stability Minimum [°C]	Temperature Stability Maximum [°C]	Comment	Organism
50	-	30 min, stable	Serratia marcescens

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7.5	-	-	Serratia marcescens

Cofactor

Cofactor	Comment	Organism	Structure
FAD	required	Serratia marcescens

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.1	-	Val	-	Serratia marcescens
1	-	Leu	-	Serratia marcescens
1	-	Ile	-	Serratia marcescens

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Release 2023.1 (January 2023)