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Literature summary for 2.2.1.7 extracted from

  • Schürmann, M.; Schürmann, M.; Sprenger, G.A.
    Fructose 6-phosphate aldolase and 1-deoxy-D-xylulose 5-phosphate synthase from Escherichia coli as tools in enzymatic synthesis of 1-deoxysugars (2002), J. Mol. Catal. B, 19-20, 247-252.
No PubMed abstract available

Cloned(Commentary)

Cloned (Comment) Organism
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Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pyruvate + D-glyceraldehyde Escherichia coli the reaction product, 1-deoxy-D-xylulose 5-phosphate, is a precursor to isoprenoids and vitamins 1-deoxy-D-xylulose + CO2
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?

Organism

Organism UniProt Comment Textmining
Escherichia coli
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
hydroxypyruvate + D-glyceraldehyde 3-phosphate 7.2% of the activity with pyruvate Escherichia coli D-xylulose 5-phosphate + CO2
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pyruvate + D-erythrose 17% of the activity with D-glyceraldehyde Escherichia coli 1-deoxy-D-fructose + CO2
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?
pyruvate + D-erythrose 4-phosphate 84% of the activity with D-glyceraldehyde Escherichia coli 1-deoxy-D-fructose 6-phosphate + CO2
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?
pyruvate + D-glyceraldehyde the reaction product, 1-deoxy-D-xylulose 5-phosphate, is a precursor to isoprenoids and vitamins Escherichia coli 1-deoxy-D-xylulose + CO2
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pyruvate + D-glyceraldehyde as active as D-glyceraldehyde 3-phosphate Escherichia coli 1-deoxy-D-xylulose + CO2
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pyruvate + D-glyceraldehyde 3-phosphate
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Escherichia coli 1-deoxy-D-xylulose 5-phosphate + CO2
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?
pyruvate + glycolaldehyde 71% of the activity with D-glyceraldehyde Escherichia coli 1-deoxy-L-erythrulose + CO2
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?