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Literature summary for 2.3.1.135 extracted from

  • MacDonald, P.N.; Ong, D.E.
    A lecithin:retinol acyltransferase activity in human and rat liver (1988), Biochem. Biophys. Res. Commun., 156, 157-163.
    View publication on PubMed
Search for more literature for 2.3.1.135

Inhibitors

Inhibitors Comment Organism Structure
N-ethylmaleimide 0.001 mM, complete inhibition of retinol-(cellular-retinol-binding-protein)type II esterification Homo sapiens
N-ethylmaleimide
-
 Rattus norvegicus
phenylmethylsulfonyl fluoride 2 mM, 90% inhibition of retinol-(cellular-retinol-binding-protein)type II esterification Homo sapiens
phenylmethylsulfonyl fluoride
-
 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0005
-
 retinol-(cellular-retinol-binding-protein) reaction with phosphatidylcholine Homo sapiens
0.001
-
 retinol-[cellular-retinol-binding-protein] liver LRAT, reaction with phosphatidylcholine Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Homo sapiens
-
-
microsome
-
 Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information little or no ability to transfer acyl groups from lysophosphatidylcholine, phosphatidylethanolamine or phosphatidic acid to retinol-(cellular-retinol-binding protein) Homo sapiens ?
-
 ?
additional information little or no ability to transfer acyl groups from lysophosphatidylcholine, phosphatidylethanolamine or phosphatidic acid to retinol-(cellular-retinol-binding protein) Rattus norvegicus ?
-
 ?
additional information only fatty acyl group at the sn-1 is transferred Homo sapiens ?
-
 ?
additional information only fatty acyl group at the sn-1 is transferred Rattus norvegicus ?
-
 ?
additional information phosphatidylcholine selective Homo sapiens ?
-
 ?
additional information phosphatidylcholine selective Rattus norvegicus ?
-
 ?
phosphatidylcholine + retinol-(cellular-retinol-binding-protein)
-
 Homo sapiens 2-acylglycerophosphocholine + retinyl ester-(cellular-retinol-binding-protein)
-
 ?
phosphatidylcholine + retinol-(cellular-retinol-binding-protein)
-
 Rattus norvegicus 2-acylglycerophosphocholine + retinyl ester-(cellular-retinol-binding-protein)
-
 ?
phosphatidylcholine + retinol-[cellular-retinol-binding-protein]
-
 Rattus norvegicus 2-acylglycerophosphocholine + retinyl-ester-[cellular-retinol-binding-protein]
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
-
 Homo sapiens
37
-
-
 Rattus norvegicus