Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | localized to synaptic membranes | Mus musculus | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q8VDZ4 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hippocampus | expression in the hippocampal subfield CA3 and the dentate gyrus | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
DHHC5 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | mice homozygous for DHHC5, are born at half the expected rate, and survivors show a marked deficit in contextual fear conditioning, an indicator of defective hippocampal-dependent learning. DHHC5 is highly enriched in a post-synaptic density preparation and co-immunoprecipitates with post-synaptic density protein PSD-95, an interaction that is mediated through binding of the carboxyl terminus of DHHC5 and the PDZ3 domain of PSD-95 | Mus musculus |