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Literature summary for 2.3.1.256 extracted from

  • Starheim, K.; Gromyko, D.; Evjenth, R.; Ryningen, A.; Varhaug, J.; Lillehaug, J.; Arnesen, T.
    Knockdown of human Nalpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localization (2009), Mol. Cell. Biol., 29, 3569-3581.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.256

Localization

Localization Comment Organism GeneOntology No. Textmining
ribosome
-
 Homo sapiens 5840
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl-CoA + an N-terminal-L-methionyl-L-leucyl-[Arl8b protein] Homo sapiens high activity, the full sequence is MLALISRRWGRPVGRRRRPVRVYP an N-terminal-Nalpha-acetyl-L-methionyl-L-leucyl-[Arl8b protein] + CoA
-
 ?
acetyl-CoA + an N-terminal-L-methionyl-L-leucyl-[mTOR protein] Homo sapiens highest activity. The full sequence is MLGTGPARWGRPVGRRRRPVRVYP an N-terminal-Nalpha-acetyl-L-methionyl-L-leucyl-[mTOR protein] + CoA
-
 ?
acetyl-CoA + an N-terminal-L-methionyl-L-leucyl-[RNP F protein] Homo sapiens the full sequence is MLGTEGGRWGRPVGRRRRPVRVYP an N-terminal-Nalpha-acetyl-L-methionyl-L-leucyl-[RNP F protein] + CoA
-
 ?
acetyl-CoA + an N-terminal-L-methionyl-L-leucyl-[RNP H protein] Homo sapiens high activity, the full sequence is MLGTEGGRWGRPVGRRRRPVRVYP an N-terminal-Nalpha-acetyl-L-methionyl-L-leucyl-[RNP H protein] + CoA
-
 ?
additional information Homo sapiens almost no activity with nuclear factor kappaB p65 (MDELFPLRWGRPVGRRRRPVRVYP), kinesin KIF4A (MKEEVKGRWGRPVGRRRRPVRVYP), and high-mobility group protein A1 (SESSSKSRWGRPVGRRRRPVRVYP) ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q147X3
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + an N-terminal-L-methionyl-L-leucyl-[Arl8b protein] high activity, the full sequence is MLALISRRWGRPVGRRRRPVRVYP Homo sapiens an N-terminal-Nalpha-acetyl-L-methionyl-L-leucyl-[Arl8b protein] + CoA
-
 ?
acetyl-CoA + an N-terminal-L-methionyl-L-leucyl-[mTOR protein] highest activity. The full sequence is MLGTGPARWGRPVGRRRRPVRVYP Homo sapiens an N-terminal-Nalpha-acetyl-L-methionyl-L-leucyl-[mTOR protein] + CoA
-
 ?
acetyl-CoA + an N-terminal-L-methionyl-L-leucyl-[RNP F protein] the full sequence is MLGTEGGRWGRPVGRRRRPVRVYP Homo sapiens an N-terminal-Nalpha-acetyl-L-methionyl-L-leucyl-[RNP F protein] + CoA
-
 ?
acetyl-CoA + an N-terminal-L-methionyl-L-leucyl-[RNP H protein] high activity, the full sequence is MLGTEGGRWGRPVGRRRRPVRVYP Homo sapiens an N-terminal-Nalpha-acetyl-L-methionyl-L-leucyl-[RNP H protein] + CoA
-
 ?
additional information almost no activity with nuclear factor kappaB p65 (MDELFPLRWGRPVGRRRRPVRVYP), kinesin KIF4A (MKEEVKGRWGRPVGRRRRPVRVYP), and high-mobility group protein A1 (SESSSKSRWGRPVGRRRRPVRVYP) Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
MAK10 auxiliary subunit Homo sapiens
MAK3 catalytic subunit Homo sapiens
MAK31 auxiliary subunit Homo sapiens
Nalpha-terminal acetyltransferase complex C
-
 Homo sapiens
NatC
-
 Homo sapiens

General Information

General Information Comment Organism
malfunction knockdown of Nalpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant Arf-like GTPase Arl8b localization Homo sapiens