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Literature summary for 2.3.1.30 extracted from

  • Kumaran, S.; Jez, J.M.
    Thermodynamics of the interaction between O-acetylserine sulfhydrylase and the C-terminus of serine acetyltransferase (2007), Biochemistry, 46, 5586-5594.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information the thermodynamics of formation of a complex of Arabidopsis thaliana O-acetylserine sulfhydrylase and the C-terminal ligand of AtSAT (C10 peptide) as a function of temperature and salt concentration using fluorescence spectroscopy and isothermal titration calorimetry is analysed. Results show that the C-terminus of AtSAT provides the major contribution to the total binding energy in the plant cysteine synthase complex. The C10 peptide binds to the O-acetylserine sulfhydrylase homodimer in a 2:1 complex. Interaction between AtOASS and the C10 peptide is tight (Kd: 5-100 nM) over a range of temperatures (10-35°C) and NaCl concentrations (0.02-1.3 M) Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
plastid
-
Arabidopsis thaliana 9536
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl-CoA + L-serine Arabidopsis thaliana cysteine biosynthesis in plants is partly regulated by the physical association of O-acetylserine sulfhydrylase and serine acetyltransferase. Thermodynamics of the interaction is analyzed CoA + O-acetyl-L-serine
-
?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + L-serine cysteine biosynthesis in plants is partly regulated by the physical association of O-acetylserine sulfhydrylase and serine acetyltransferase. Thermodynamics of the interaction is analyzed Arabidopsis thaliana CoA + O-acetyl-L-serine
-
?

Synonyms

Synonyms Comment Organism
AtOASS
-
Arabidopsis thaliana
AtSAT
-
Arabidopsis thaliana
serine O-acetyltransferase
-
Arabidopsis thaliana