Cloned (Comment) | Organism |
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when the gene is overexpressed with a vector plasmid p426Gal1 in the wild type Saccharomyces cerevisiae as a host, the recombinant yeast, which shows more than 100 times higher D-amino acid-N-acetyltransferase activity than the wild type, is much more tolerant to D-amino acids than the wild type | Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + a D-amino acid | Saccharomyces cerevisiae | D-amino acids are toxic to Saccharomyces cerevisiae but are detoxified with D-amino acid-N-acetyltransferase by N-acetylation preceding removal from yeast cells | CoA + an N-acetyl-D-amino acid | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + a D-amino acid | D-amino acids are toxic to Saccharomyces cerevisiae but are detoxified with D-amino acid-N-acetyltransferase by N-acetylation preceding removal from yeast cells | Saccharomyces cerevisiae | CoA + an N-acetyl-D-amino acid | - |
? |