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Literature summary for 2.3.1.5 extracted from

  • Paul, R.C.; Ratledge, C.
    Further studies on anthranilate N-acetyltransferase and the metabolism of N-acetylanthranilic acid in Aerobacter aerogenes (1973), Biochim. Biophys. Acta, 320, 9-15.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
glucosamine
-
Klebsiella aerogenes
glucosamine 6-phosphate
-
Klebsiella aerogenes
iodoacetic acid
-
Klebsiella aerogenes
N-ethylmaleimide
-
Klebsiella aerogenes
p-chloromercuribenzoate
-
Klebsiella aerogenes
propionyl-CoA
-
Klebsiella aerogenes
salicylic acid
-
Klebsiella aerogenes

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
12.5
-
3-aminobenzoic acid
-
Klebsiella aerogenes
13
-
2-aminobenzoic acid
-
Klebsiella aerogenes

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl-CoA + an arylamine Klebsiella aerogenes constitutive enzyme CoA + a N-acetylarylamine
-
?

Organism

Organism UniProt Comment Textmining
Klebsiella aerogenes
-
-
-
Klebsiella aerogenes N5-36
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Klebsiella aerogenes

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + 2-aminobenzoic acid i.e. anthranilate, ir Klebsiella aerogenes CoA + N-acetylanthranilate
-
ir
acetyl-CoA + 3-aminobenzoic acid
-
Klebsiella aerogenes CoA + N-acetyl-3-aminobenzoic acid
-
?
acetyl-CoA + 4-aminobenzoic acid poor Klebsiella aerogenes CoA + 4-acetylaminobenzoic acid
-
?
acetyl-CoA + 4-aminobenzoic acid poor Klebsiella aerogenes N5-36 CoA + 4-acetylaminobenzoic acid
-
?
acetyl-CoA + an arylamine constitutive enzyme Klebsiella aerogenes CoA + a N-acetylarylamine
-
?
acetyl-CoA + aniline
-
Klebsiella aerogenes CoA + acetanilide
-
?
acetyl-CoA + aniline
-
Klebsiella aerogenes N5-36 CoA + acetanilide
-
?
additional information not butyryl-CoA Klebsiella aerogenes ?
-
?
additional information no substrate: glucosamine 6-phosphate Klebsiella aerogenes ?
-
?
additional information propionyl-CoA can replace acetyl-CoA Klebsiella aerogenes ?
-
?
additional information not butyryl-CoA Klebsiella aerogenes N5-36 ?
-
?
additional information no substrate: glucosamine 6-phosphate Klebsiella aerogenes N5-36 ?
-
?
additional information propionyl-CoA can replace acetyl-CoA Klebsiella aerogenes N5-36 ?
-
?