Literature summary for 2.3.1.51 extracted from

Li, X.; Liu, L.; Ji, J.; Chen, Q.; Hua, X.; Jiang, Y.; Feng, Y.; Yu, Y.
Tigecycline resistance in Acinetobacter baumannii mediated by frameshift mutation in plsC, encoding 1-acyl-sn-glycerol-3-phosphate acyltransferase (2015), Eur. J. Clin. Microbiol. Infect. Dis., 34, 625-631 .

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Organism

Organism	UniProt	Comment	Textmining
Acinetobacter baumannii	-	-	-

Synonyms

Synonyms	Comment	Organism
PlsC	-	Acinetobacter baumannii

General Information

General Information	Comment	Organism
metabolism	plsC plays an important role in tigecycline resistance. Tigecycline resistance in Acinetobacter baumannii is mediated by frameshift mutation in plsC. Change in the cellular membrane caused by plsC mutation is detected by flow cytometry. It is concluded that cellular membrane change may play an important role in tigecycline resistance in Acinetobacter baumannii	Acinetobacter baumannii

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Release 2023.1 (January 2023)