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Literature summary for 2.3.1.6 extracted from

  • Emson, P.C.; Malthe-Soerenssen, D.; Fonnum, F.
    Purification and properties of choline acetyltransferase from the nervous system of different invertebrates (1974), J. Neurochem., 22, 1089-1098.
    View publication on PubMed
Search for more literature for 2.3.1.6

Activating Compound

Activating Compound Comment Organism Structure
KCl
-
 Limulus polyphemus
KCl
-
 Cornu aspersum
KCl
-
 Periplaneta americana
NaCl
-
 Limulus polyphemus
NaCl
-
 Cornu aspersum
NaCl
-
 Periplaneta americana

Inhibitors

Inhibitors Comment Organism Structure
3-Bromoacetonyltrimethylammonium ion
-
 Cornu aspersum
3-Bromoacetonyltrimethylammonium ion
-
 Limulus polyphemus
3-Bromoacetonyltrimethylammonium ion
-
 Periplaneta americana
5,5'-dithiobis(2-nitrobenzoate)
-
 Cornu aspersum
5,5'-dithiobis(2-nitrobenzoate)
-
 Limulus polyphemus
5,5'-dithiobis(2-nitrobenzoate)
-
 Periplaneta americana
Acetylcholine competitive to choline, non-competitive to acetyl-CoA Cornu aspersum
Acetylcholine competitive to choline, non-competitive to acetyl-CoA Limulus polyphemus
Acetylcholine competitive to choline, non-competitive to acetyl-CoA Periplaneta americana
Acyloylcholine
-
 Cornu aspersum
Acyloylcholine
-
 Limulus polyphemus
Acyloylcholine
-
 Periplaneta americana
Chloroacetylcholine
-
 Cornu aspersum
Chloroacetylcholine
-
 Limulus polyphemus
Chloroacetylcholine
-
 Periplaneta americana
CoA competitive to acetyl-CoA, non-competitive to choline Cornu aspersum
CoA competitive to acetyl-CoA, non-competitive to choline Limulus polyphemus
CoA competitive to acetyl-CoA, non-competitive to choline Periplaneta americana
iodoacetate
-
 Cornu aspersum
iodoacetate
-
 Limulus polyphemus
iodoacetate
-
 Periplaneta americana

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.016
-
 acetyl-CoA
-
 Periplaneta americana
0.051
-
 acetyl-CoA
-
 Cornu aspersum
0.068
-
 acetyl-CoA
-
 Limulus polyphemus
0.37
-
 choline
-
 Cornu aspersum
0.55
-
 choline
-
 Periplaneta americana
27
-
 choline
-
 Limulus polyphemus

Organism

Organism UniProt Comment Textmining
Cornu aspersum
-
 snail
-
Limulus polyphemus
-
 horseshoe crab
-
Periplaneta americana
-
 cockroach
-

Purification (Commentary)

Purification (Comment) Organism
-
 Limulus polyphemus
-
 Cornu aspersum
-
 Periplaneta americana

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + choline
-
 Limulus polyphemus acetylcholine + CoA
-
 ?
acetyl-CoA + choline
-
 Cornu aspersum acetylcholine + CoA
-
 ?
acetyl-CoA + choline
-
 Periplaneta americana acetylcholine + CoA
-
 ?