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Literature summary for 2.3.1.6 extracted from

  • de Sales Santos, I.M.; Feitosa, C.M.; de Freitas, R.M.
    Pilocarpine-induced seizures produce alterations on choline acetyltransferase and acetylcholinesterase activities and deficit memory in rats (2010), Cell. Mol. Neurobiol., 30, 569-575.
    View publication on PubMed
Search for more literature for 2.3.1.6

Inhibitors

Inhibitors Comment Organism Structure
pilocarpine pilocarpine-induced seizures reduce choline acetyltransferase activity in the hippocampus, overview Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl-CoA + choline Rattus norvegicus
-
 CoA + O-acetylcholine
-
 ?
additional information Rattus norvegicus pilocarpine-induced seizures produce alterations on choline acetyltransferase and acetylcholinesterase activities and deficit memory in rats, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 male Wistar rats
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-
hippocampus ChAt activity in untreated and in pilocarpine-treated hippocampi, overview Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + choline
-
 Rattus norvegicus CoA + O-acetylcholine
-
 ?
additional information pilocarpine-induced seizures produce alterations on choline acetyltransferase and acetylcholinesterase activities and deficit memory in rats, overview Rattus norvegicus ?
-
 ?

Synonyms

Synonyms Comment Organism
ChAT
-
 Rattus norvegicus
choline acetyltransferase
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
acetyl-CoA
-
 Rattus norvegicus