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Literature summary for 2.3.1.7 extracted from

  • Saeed, A.; McMillin, J.B.; Wolkowicz, P.E.; Brouillette, W.J.
    Carnitine acyltransferase enzymic catalysis requires a positive charge on the carnitine cofactor (1993), Arch. Biochem. Biophys., 305, 307-312.
    View publication on PubMed
Search for more literature for 2.3.1.7

Inhibitors

Inhibitors Comment Organism Structure
3-acetoxy-5,5-dimethylhexanoic acid
-
 Columba sp.
3-hydroxy-5,5-dimethylhexanoic acid
-
 Columba sp.
R-(+)-3-hydroxy-5,5-dimethylhexanoic acid
-
 Columba sp.
S-(-)-3-hydroxy-5,5-dimethylhexanoic acid
-
 Columba sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl-CoA + carnitine Columba sp.
-
 O-acetylcarnitine + CoASH
-
 r
acyl-CoA + carnitine Columba sp.
-
 acylcarnitine + CoASH
-
 r
acylcarnitine + CoASH Columba sp.
-
 acyl-CoA + carnitine
-
 r
O-acetylcarnitine + CoASH Columba sp.
-
 acetyl-CoA + carnitine
-
 r

Organism

Organism UniProt Comment Textmining
Columba sp.
-
 pigeon
-
Columba sp.
-
 commercial preparation, Sigma
-

Source Tissue

Source Tissue Comment Organism Textmining
breast muscle
-
 Columba sp.
-
muscle
-
 Columba sp.
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + carnitine
-
 Columba sp. O-acetylcarnitine + CoASH
-
 r
acetyl-CoA + L-(-)carnitine
-
 Columba sp. O-acetylcarnitine + CoASH
-
 r
acyl-CoA + carnitine
-
 Columba sp. acylcarnitine + CoASH
-
 r
acylcarnitine + CoASH
-
 Columba sp. acyl-CoA + carnitine
-
 r
additional information 3-hydroxy-5,5-dimethylhexanoic acid, 3-acetoxy-5,5-dimethylhexanoic acid, R-(+)-3-hydroxy-5,5-dimethylhexanoic acid and S-(-)-3-hydroxy-5,5-dimethylhexanoic acid are not substrates Columba sp. ?
-
 ?
additional information D-carnitine is no substrate Columba sp. ?
-
 ?
O-acetylcarnitine + CoASH
-
 Columba sp. acetyl-CoA + L-(-)carnitine
-
 r
O-acetylcarnitine + CoASH
-
 Columba sp. acetyl-CoA + carnitine
-
 r

Synonyms

Synonyms Comment Organism
CAT
-
 Columba sp.

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
4.1
-
 3-acetoxy-5,5-dimethylhexanoic acid reverse direction Columba sp.
7.5
-
 S-(-)-3-hydroxy-5,5-dimethylhexanoic acid
-
 Columba sp.
8.3
-
 3-hydroxy-5,5-dimethylhexanoic acid
-
 Columba sp.
20.3
-
 R-(+)-3-hydroxy-5,5-dimethylhexanoic acid
-
 Columba sp.