Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | sequence contains a N-terminal mitochondrial targeting sequence and a C-terminal peroxisomal targeting sequence and protein is localized to both peroxisomes and mitochondria | Aspergillus nidulans | 5739 | - |
peroxisome | sequence contains a N-terminal mitochondrial targeting sequence and a C-terminal peroxisomal targeting sequence and protein is localized to both peroxisomes and mitochondria | Aspergillus nidulans | 5777 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
68500 | - |
x * 68500, calculated | Aspergillus nidulans |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus nidulans | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | sequence contains a N-terminal mitochondrial targeting sequence and a C-terminal peroxisomal targeting sequence and protein is localized to both peroxisomes and mitochondria | Aspergillus nidulans |
Subunits | Comment | Organism |
---|---|---|
? | x * 68500, calculated | Aspergillus nidulans |
Synonyms | Comment | Organism |
---|---|---|
acuJ | - |
Aspergillus nidulans |
General Information | Comment | Organism |
---|---|---|
physiological function | protein is essential for growth on fatty acids as well as acetate. Mislocalization of the enzyme to the cytoplasm does not result in loss of growth on acetate but prevents growth on fatty acids. The mitochondrial enzyme is essential for the transfer of acetyl units to mitochondria, peroxisomal localization is required only for transfer from peroxisomes to mitochondria. Peroxisomal enzyme is not required for the import of acetyl-CoA into peroxisomes for conversion to malate by malate synthase, and export of acetyl-CoA from peroxisomes to the cytoplasm is independent of FacC when malate synthase is mislocalized to the cytoplasm | Aspergillus nidulans |