KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | Km-values for several acceptors in diabetic and control rats, female and male, with donors L-Glu-4-nitroanilide and L-5-glutamyl-(7-amido-4-methylcoumarin) | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(5-L-glutamyl)-peptide + acceptor + H+ | Rattus norvegicus | - |
peptide + 5-L-glutamyl amino acid | - |
? | |
additional information | Rattus norvegicus | activity in induced diabetic rats is higher than in control rats and higher in male than in female rats | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
streptozotocin-induced diabetic, female and male | - |
Purification (Comment) | Organism |
---|---|
from normal and diabetic rat liver | Rattus norvegicus |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
a (5-L-glutamyl)-peptide + an amino acid = a peptide + a 5-L-glutamyl amino acid | kinetic study | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | normal and induced enzyme activity, not expression level, by streptozotocin diabetes induced in rats | Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
activity in induced diabetic rats is higher than in control rats and higher in male than in female rats | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(5-L-glutamyl)-peptide + acceptor + H+ | - |
Rattus norvegicus | peptide + 5-L-glutamyl amino acid | - |
? | |
5-L-glutamyl-4-nitroanilide + glycylglycine | - |
Rattus norvegicus | 4-nitroaniline + 5-L-glutamylglycylglycine | - |
? | |
5-L-glutamyl-4-nitroanilide + L-alanine | - |
Rattus norvegicus | 4-nitroaniline + 5-L-glutamyl-L-alanine | - |
? | |
5-L-glutamyl-4-nitroanilide + L-alanylglycine | - |
Rattus norvegicus | 4-nitroaniline + 5-L-glutamyl-L-alanylglycine | - |
? | |
5-L-glutamyl-4-nitroanilide + L-aspartate | - |
Rattus norvegicus | 4-nitroaniline + 5-L-glutamyl-L-aspartate | - |
? | |
5-L-glutamyl-4-nitroanilide + L-glutamate | - |
Rattus norvegicus | 4-nitroaniline + 5-L-glutamyl-L-glutamate | - |
? | |
5-L-glutamyl-4-nitroanilide + L-glutamine | - |
Rattus norvegicus | 4-nitroaniline + 5-L-glutamyl-L-glutamine | - |
? | |
5-L-glutamyl-4-nitroanilide + L-methionine | - |
Rattus norvegicus | 4-nitroaniline + 5-L-glutamyl-L-methionine | - |
? | |
5-L-glutamyl-4-nitroanilide + L-phenylalanine | - |
Rattus norvegicus | 4-nitroaniline + 5-L-glutamyl-L-phenylalanine | - |
? | |
5-L-glutamyl-7-amido-4-methylcoumarin + acceptor | acceptors are amino acids and peptides, overview | Rattus norvegicus | 7-amino-4-methylcoumarin + 5-L-glutamyl-acceptor | - |
? | |
additional information | activity in induced diabetic rats is higher than in control rats and higher in male than in female rats | Rattus norvegicus | ? | - |
? |