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Literature summary for 2.3.3.5 extracted from

  • Watson, D.; Lindel, D.L.; Fall, R.
    Pseudomonas aeruginosa contains an inducible methylcitrate synthase (1983), Curr. Microbiol., 8, 17-21.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
propanoyl-CoA + H2O + oxaloacetate Pseudomonas putida
-
2-methylcitrate + CoA
-
?
propanoyl-CoA + H2O + oxaloacetate Pseudomonas citronellolis
-
2-methylcitrate + CoA
-
?
propanoyl-CoA + H2O + oxaloacetate Pseudomonas aeruginosa first key enzyme of the methylcitric acid cycle 2-methylcitrate + CoA
-
?
propanoyl-CoA + H2O + oxaloacetate Yarrowia lipolytica first key enzyme of the methylcitric acid cycle 2-methylcitrate + CoA
-
?
propanoyl-CoA + H2O + oxaloacetate Pseudomonas aeruginosa PAO first key enzyme of the methylcitric acid cycle 2-methylcitrate + CoA
-
?

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa
-
PAO
-
Pseudomonas aeruginosa PAO
-
PAO
-
Pseudomonas citronellolis
-
-
-
Pseudomonas putida
-
-
-
Yarrowia lipolytica
-
formerly Candida lipolytica
-

Purification (Commentary)

Purification (Comment) Organism
partially Pseudomonas aeruginosa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + H2O + oxaloacetate uses acetyl-CoA in preference to propionyl-CoA Yarrowia lipolytica citrate + CoA
-
?
additional information constitutive Yarrowia lipolytica ?
-
?
additional information enzyme is induced by growth on propionate, propanol and heptanoate Pseudomonas aeruginosa ?
-
?
additional information enzyme is relatively specific for its acetyl-CoA substrate, utilizing propionyl-CoA and not acetyl-CoA Pseudomonas aeruginosa ?
-
?
additional information enzyme is induced by growth on propionate, propanol and heptanoate Pseudomonas aeruginosa PAO ?
-
?
additional information enzyme is relatively specific for its acetyl-CoA substrate, utilizing propionyl-CoA and not acetyl-CoA Pseudomonas aeruginosa PAO ?
-
?
propanoyl-CoA + H2O + oxaloacetate
-
Pseudomonas aeruginosa 2-methylcitrate + CoA
-
?
propanoyl-CoA + H2O + oxaloacetate
-
Yarrowia lipolytica 2-methylcitrate + CoA
-
?
propanoyl-CoA + H2O + oxaloacetate
-
Pseudomonas putida 2-methylcitrate + CoA
-
?
propanoyl-CoA + H2O + oxaloacetate
-
Pseudomonas citronellolis 2-methylcitrate + CoA
-
?
propanoyl-CoA + H2O + oxaloacetate first key enzyme of the methylcitric acid cycle Pseudomonas aeruginosa 2-methylcitrate + CoA
-
?
propanoyl-CoA + H2O + oxaloacetate first key enzyme of the methylcitric acid cycle Yarrowia lipolytica 2-methylcitrate + CoA
-
?
propanoyl-CoA + H2O + oxaloacetate
-
Pseudomonas aeruginosa PAO 2-methylcitrate + CoA
-
?
propanoyl-CoA + H2O + oxaloacetate first key enzyme of the methylcitric acid cycle Pseudomonas aeruginosa PAO 2-methylcitrate + CoA
-
?