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Literature summary for 2.3.3.8 extracted from

  • Hoffmann, G.E.; Andres, H.; Weiss, L.; Kreisel, C.; Sander, R.
    Properties and organ distribution of ATP citrate (pro-3S)-lyase (1980), Biochim. Biophys. Acta, 620, 151-158.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.011
-
CoA
-
Homo sapiens
0.011
-
CoA
-
Rattus norvegicus
0.12
-
citrate
-
Homo sapiens
1.3
-
citrate
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
adipose tissue
-
Homo sapiens
-
adipose tissue
-
Rattus norvegicus
-
adipose tissue low activity Gallus gallus
-
adrenal gland
-
Homo sapiens
-
adrenal gland
-
Rattus norvegicus
-
colon
-
Gallus gallus
-
colon
-
Homo sapiens
-
colon
-
Rattus norvegicus
-
ileum
-
Gallus gallus
-
ileum
-
Homo sapiens
-
ileum
-
Rattus norvegicus
-
jejunum
-
Gallus gallus
-
jejunum
-
Homo sapiens
-
jejunum
-
Rattus norvegicus
-
liver
-
Gallus gallus
-
liver
-
Homo sapiens
-
liver
-
Rattus norvegicus
-

Storage Stability

Storage Stability Organism
-20°C, pH 8 stable for 4 months Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + citrate + CoA
-
Gallus gallus ADP + phosphate + acetyl-CoA + oxaloacetate
-
?
ATP + citrate + CoA
-
Homo sapiens ADP + phosphate + acetyl-CoA + oxaloacetate
-
?
ATP + citrate + CoA
-
Rattus norvegicus ADP + phosphate + acetyl-CoA + oxaloacetate
-
?