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Literature summary for 2.3.3.8 extracted from
- Compartmentation of ATP:citrate lyase in plants (2000), Plant Physiol., 122, 1225-1230.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | enzyme is mainly cytosolic | Spinacia oleracea | 5829 | - |
| cytosol | enzyme is mainly cytosolic | Pisum sativum | 5829 | - |
| cytosol | enzyme is mainly cytosolic | Nicotiana tabacum | 5829 | - |
| cytosol | enzyme is mainly cytosolic | Brassica napus | 5829 | - |
| plastid | predominantly localized in plastids | Spinacia oleracea | 9536 | - |
| plastid | predominantly localized in plastids | Brassica napus | 9536 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 120000 | - |
x * 120000, SDS-PAGE | Spinacia oleracea |
| 120000 | - |
x * 120000, SDS-PAGE | Brassica napus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + citrate + CoA | Spinacia oleracea | the cytosolic enzyme may provide acetyl-coenzyme A for the mevalonate pathway or fatty acid elongation | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? |  |
| ATP + citrate + CoA | Pisum sativum | the cytosolic enzyme may provide acetyl-coenzyme A for the mevalonate pathway or fatty acid elongation | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? | |
| ATP + citrate + CoA | Nicotiana tabacum | the cytosolic enzyme may provide acetyl-coenzyme A for the mevalonate pathway or fatty acid elongation | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? | |
| ATP + citrate + CoA | Brassica napus | the cytosolic enzyme may provide acetyl-coenzyme A for the mevalonate pathway or fatty acid elongation | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? | |
| ATP + citrate + CoA | Spinacia oleracea | the plastidic enzyme is proposed to function for the supply of acetyl-coenzyme A for lipid biosynthesis de novo | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? | |
| ATP + citrate + CoA | Brassica napus | the plastidic enzyme is proposed to function for the supply of acetyl-coenzyme A for lipid biosynthesis de novo | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Brassica napus | - |
- |
- |
| Nicotiana tabacum | - |
- |
- |
| Pisum sativum | - |
- |
- |
| Spinacia oleracea | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leaf | young | Spinacia oleracea | - |
| leaf | young | Pisum sativum | - |
| leaf | young | Nicotiana tabacum | - |
| leaf | young | Brassica napus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + citrate + CoA | - |
Spinacia oleracea | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? | |
| ATP + citrate + CoA | - |
Pisum sativum | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? | |
| ATP + citrate + CoA | - |
Nicotiana tabacum | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? | |
| ATP + citrate + CoA | - |
Brassica napus | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? | |
| ATP + citrate + CoA | the cytosolic enzyme may provide acetyl-coenzyme A for the mevalonate pathway or fatty acid elongation | Spinacia oleracea | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? | |
| ATP + citrate + CoA | the cytosolic enzyme may provide acetyl-coenzyme A for the mevalonate pathway or fatty acid elongation | Pisum sativum | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? | |
| ATP + citrate + CoA | the cytosolic enzyme may provide acetyl-coenzyme A for the mevalonate pathway or fatty acid elongation | Nicotiana tabacum | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? | |
| ATP + citrate + CoA | the cytosolic enzyme may provide acetyl-coenzyme A for the mevalonate pathway or fatty acid elongation | Brassica napus | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? | |
| ATP + citrate + CoA | the plastidic enzyme is proposed to function for the supply of acetyl-coenzyme A for lipid biosynthesis de novo | Spinacia oleracea | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? | |
| ATP + citrate + CoA | the plastidic enzyme is proposed to function for the supply of acetyl-coenzyme A for lipid biosynthesis de novo | Brassica napus | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 120000, SDS-PAGE | Spinacia oleracea |
| ? | x * 120000, SDS-PAGE | Brassica napus |
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