Literature summary for 2.3.3.8 extracted from

Wei, X.; Schultz, K.; Bazilevsky, G.A.; Vogt, A.; Marmorstein, R.
Molecular basis for acetyl-CoA production by ATP-citrate lyase (2020), Nat. Struct. Mol. Biol., 27, 33-41 .

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + citrate + CoA	Homo sapiens	the enzyme synthesizes cytosolic acetyl coenzyme A (acetyl-CoA), a fundamental cellular building block	ADP + phosphate + acetyl-CoA + oxaloacetate	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P53396	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + citrate + CoA	-	Homo sapiens	ADP + phosphate + acetyl-CoA + oxaloacetate	-	?
ATP + citrate + CoA	the enzyme synthesizes cytosolic acetyl coenzyme A (acetyl-CoA), a fundamental cellular building block	Homo sapiens	ADP + phosphate + acetyl-CoA + oxaloacetate	-	?

Synonyms

Synonyms	Comment	Organism
ACLY	-	Homo sapiens
ATP-citrate lyase	-	Homo sapiens

General Information

General Information	Comment	Organism
metabolism	the enzyme synthesizes cytosolic acetyl coenzyme A (acetyl-CoA), a fundamental cellular building block	Homo sapiens

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Release 2023.1 (January 2023)