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Literature summary for 2.4.1.15 extracted from

  • Gibson, R.P.; Turkenburg, J.P.; Charnock, S.J.; Lloyd, R.; Davies, G.J.
    Insights into trehalose synthesis provided by the structure of the retaining glucosyltransferase OtsA (2002), Chem. Biol., 9, 1337-1346 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli B834(DE3) cells Escherichia coli

Crystallization (Commentary)

Crystallization (Comment) Organism
in complex with UDP and D-glucose 6-phosphate, using 14% (w/v) PEG 4000, 0.15 M NaOAc, 0.1 M imidazole buffer (pH 7.5), and 200 mM NaCl Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-alpha-D-glucose + D-glucose 6-phosphate Escherichia coli
-
UDP + alpha,alpha-trehalose 6-phosphate
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli P31677
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-alpha-D-glucose + D-glucose 6-phosphate
-
Escherichia coli UDP + alpha,alpha-trehalose 6-phosphate
-
?

Synonyms

Synonyms Comment Organism
OtsA
-
Escherichia coli