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Literature summary for 2.4.1.152 extracted from
- Characterization and purification of fucosyltransferases from the cytosol of rat colon (1996), Int. J. Biochem. Cell Biol., 28, 165-174.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Cu2+ | - |
Rattus norvegicus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | bound to | Rattus norvegicus | 16020 | - |
| soluble | - |
Rattus norvegicus | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | Mn2+, Mg2+ or Ca2+ required | Rattus norvegicus | |
| Mg2+ | Mn2+, Mg2+ or Ca2+ required | Rattus norvegicus | |
| Mn2+ | Mn2+, Mg2+ or Ca2+ required | Rattus norvegicus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 40680 | - |
x * 40680, SDS-PAGE | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| soluble enzyme | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| colon | - |
Rattus norvegicus | - |
| jejunum | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.002289 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GDP-L-fucose + desialylated alpha1-acid glycoprotein | - |
Rattus norvegicus | GDP + ? | - |
? | |
| GDP-L-fucose + fetuin | - |
Rattus norvegicus | GDP + ? | - |
? | |
| additional information | 11 nonidentical amino acids, found within a hypervariable peptide segment positioned at the NH2 terminus determines whether or not an alpha(1,3)-fucosyltransferase can utilize type I acceptor substrates to form Lewis a and sialyl Lewis a moieties | Rattus norvegicus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 40680, SDS-PAGE | Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6 | - |
soluble enzyme | Rattus norvegicus |
| 6.2 | - |
membrane-bound enzyme | Rattus norvegicus |
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Release 2023.1 (January 2023)
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