Literature summary for 2.4.1.152 extracted from

Ponnampalam, A.P.; Rogers, P.A.
Expression and regulation of fucosyltransferase 4 in human endometrium (2008), Reproduction, 136, 117-123.

Search for more literature for 2.4.1.152

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
additional information	throughout the menstrual cycle, FUT4 protein is localized to glandular and luminal epithelium in the endometrium	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
alpha1,3 fucosyltransferase	-	Homo sapiens
fucosyltransferase 4	-	Homo sapiens
FUT4	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	FUT4 staining is weak in proliferative and menstrual endometrium. Inductive effect of progesterone on FUT4 transcription is lost after 48 h of treatment	down
Homo sapiens	FUT4 mRNA is significantly upregulated during the early and midsecretory stages of the menstrual cycle compared with the other menstrual phases, with maximal expression during the mid-secretory phase. In proliferative explants, progesterone significantly increases FUT4 transcription and translation after 24 h in culture. Estrogen does not have any significant effects	up

General Information

General Information	Comment	Organism
physiological function	upregulation of selectin ligands in the endometrium at the time of implantation may be mediated, at least in part, by the regulation of FUT4 expression	Homo sapiens

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Release 2023.1 (January 2023)