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Literature summary for 2.4.1.83 extracted from

  • Jensen, J.W.; Schutzbach, J.S.
    Activation of dolichyl-phospho-mannose synthase by phospholipids (1985), Eur. J. Biochem., 153, 41-48.
    View publication on PubMed
Search for more literature for 2.4.1.83

Activating Compound

Activating Compound Comment Organism Structure
additional information optimally active in a phospholipid matrix that contains some component phospholipids that prefer non-bilayer structural organization in isolation Rattus norvegicus

General Stability

General Stability Organism
unstable in presence of detergent Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
GDP 0.0013 mM, 50% inhibition Rattus norvegicus
GMP 0.016 mM, 50% inhibition Rattus norvegicus
GTP 0.003 mM, 50% inhibition Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0003
-
 dolichyl phosphate
-
 Rattus norvegicus
0.00069
-
 GDPmannose
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ divalent cation required, maximal stimulation at 2.5 mM Mn2+ Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.07
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDPmannose + dolichyl phosphate
-
 Rattus norvegicus GDP + dolichyl D-mannosyl phosphate
-
 ?