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Literature summary for 2.4.1.B51 extracted from

  • Morii, H.; Eguchi, T.; Koga, Y.
    In vitro biosynthesis of ether-type glycolipids in the methanoarchaeon Methanothermobacter thermautotrophicus (2007), J. Bacteriol., 189, 4053-4061.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
1-archaetidyl-1D-myo-inositol addition of archaetidylinositol is essential Methanothermobacter thermautotrophicus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Methanothermobacter thermautotrophicus 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ 5-10 mM activites 20% compared to Mg2+ Methanothermobacter thermautotrophicus
K+ stimulates, maximum activity at 0.5 M Methanothermobacter thermautotrophicus
Mg2+ requires 10 mM Mg2+ for maximal activity Methanothermobacter thermautotrophicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-alpha-D-glucose + 1,2-diphytanyl-sn-glycero-3-O-beta-D-glucoside Methanothermobacter thermautotrophicus the enzyme is involved in the biosynthesis of ether-type glycolipids UDP + 1,2-diphytanyl-sn-glycero-3-O-(6-O-beta-D-glucosyl)-beta-D-glucoside
-
?

Organism

Organism UniProt Comment Textmining
Methanothermobacter thermautotrophicus
-
-
-
Methanothermobacter thermautotrophicus DSM 1053
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-alpha-D-glucose + 1,2-diphytanyl-sn-glycero-3-O-beta-D-glucoside
-
Methanothermobacter thermautotrophicus UDP + 1,2-diphytanyl-sn-glycero-3-O-(6-O-beta-D-glucosyl)-beta-D-glucoside
-
?
UDP-alpha-D-glucose + 1,2-diphytanyl-sn-glycero-3-O-beta-D-glucoside the enzyme is involved in the biosynthesis of ether-type glycolipids Methanothermobacter thermautotrophicus UDP + 1,2-diphytanyl-sn-glycero-3-O-(6-O-beta-D-glucosyl)-beta-D-glucoside
-
?

Synonyms

Synonyms Comment Organism
DGA synthase
-
Methanothermobacter thermautotrophicus
MGA:UDP-glucose beta-1,6-glucosyltransferase
-
Methanothermobacter thermautotrophicus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
60
-
assay at Methanothermobacter thermautotrophicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
Methanothermobacter thermautotrophicus

pH Range

pH Minimum pH Maximum Comment Organism
6.7 8.9 pH 6.7: about 65% of maximal activity, pH 8.9: about 50% of maximal activity Methanothermobacter thermautotrophicus