Crystallization (Comment) | Organism |
---|---|
holoenzyme and catalytic subunit HisGS in complexes with substrates (5-phospho-alpha-D-ribose 1-diphosphate, 5-phospho-alpha-D-ribose 1-diphosphate-ATP, 5-phospho-alpha-D-ribose 1-diphosphate-ADP), product (N1-(5-phospho-beta-D-ribosyl)-ATP) and inhibitor (AMP), hanging drop vapor diffusion method, using 10% (w/v) polyethylene glycol 3350, 0.1 M bicine pH 8.5, 50 mM MgCl2, 0.1 M KBr, and 4% (v/v) 1,6-hexanediol | Psychrobacter arcticus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
AMP | - |
Psychrobacter arcticus | |
L-histidine | - |
Psychrobacter arcticus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | dependent on | Psychrobacter arcticus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 5-phospho-alpha-D-ribose 1-diphosphate | Psychrobacter arcticus | - |
N1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate | - |
r | |
ATP + 5-phospho-alpha-D-ribose 1-diphosphate | Psychrobacter arcticus DSM 17307 | - |
N1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Psychrobacter arcticus | Q4FQF7 | - |
- |
Psychrobacter arcticus DSM 17307 | Q4FQF7 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Psychrobacter arcticus | N1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate | - |
r | |
ATP + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Psychrobacter arcticus DSM 17307 | N1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate | - |
r |
Subunits | Comment | Organism |
---|---|---|
heterooctamer | the enzyme consist of four catalytic subunits (HisGS) and four regulatory subunits (HisZ) | Psychrobacter arcticus |
Synonyms | Comment | Organism |
---|---|---|
adenosine 5'-triphosphate phosphoribosyltransferase | - |
Psychrobacter arcticus |
ATPPRT | - |
Psychrobacter arcticus |
HisG | - |
Psychrobacter arcticus |